Annual Review of Cell and Developmental Biology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Plant Cell Wall Loosening by Expansins
Annu Rev Cell Dev Biol. 2024 May 9. doi: 10.1146/annurev-cellbio-111822-115334. Online ahead of print.ABSTRACTExpansins comprise an ancient group of cell wall proteins ubiquitous in land plants and their algal ancestors. During cell growth, they facilitate passive yielding of the wall's cellulose networks to turgor-generated tensile stresses, without evidence of enzymatic activity. Expansins are also implicated in fruit softening and other developmental processes and in adaptive responses to environmental stresses and pathogens. The major expansin families in plants include α-expansins (EXPAs), which act on cellulose-cell...
Source: Annual Review of Cell and Developmental Biology - May 9, 2024 Category: Cytology Authors: Daniel J Cosgrove Source Type: research

Ribosome Assembly and Repair
Annu Rev Cell Dev Biol. 2024 May 9. doi: 10.1146/annurev-cellbio-111822-113326. Online ahead of print.ABSTRACTRibosomes synthesize protein in all cells. Maintaining both the correct number and composition of ribosomes is critical for protein homeostasis. To address this challenge, cells have evolved intricate quality control mechanisms during assembly to ensure that only correctly matured ribosomes are released into the translating pool. However, these assembly-associated quality control mechanisms do not deal with damage that arises during the ribosomes' exceptionally long lifetimes and might equally compromise their func...
Source: Annual Review of Cell and Developmental Biology - May 9, 2024 Category: Cytology Authors: Yoon-Mo Yang Katrin Karbstein Source Type: research

What Is a Plant Cell Type in the Age of Single-Cell Biology? It's Complicated
Annu Rev Cell Dev Biol. 2024 May 9. doi: 10.1146/annurev-cellbio-111323-102412. Online ahead of print.ABSTRACTOne of the fundamental questions in developmental biology is how a cell is specified to differentiate as a specialized cell type. Traditionally, plant cell types were defined based on their function, location, morphology, and lineage. Currently, in the age of single-cell biology, researchers typically attempt to assign plant cells to cell types by clustering them based on their transcriptomes. However, because cells are dynamic entities that progress through the cell cycle and respond to signals, the transcriptome ...
Source: Annual Review of Cell and Developmental Biology - May 9, 2024 Category: Cytology Authors: Byron Rusnak Frances K Clark Batthula Vijaya Lakshmi Vadde Adrienne H K Roeder Source Type: research

Exploring Mechanical Forces Shaping Self-Organization and Morphogenesis During Early Embryo Development
Annu Rev Cell Dev Biol. 2024 Apr 12. doi: 10.1146/annurev-cellbio-120123-105748. Online ahead of print.ABSTRACTEmbryonic development is a dynamic process orchestrated by a delicate interplay of biochemical and biophysical factors. While the role of genetics and biochemistry in embryogenesis has been extensively studied, recent research has highlighted the significance of mechanical regulation in shaping and guiding this intricate process. Here, we provide an overview of the current understanding of the mechanical regulation of embryo development. We explore how mechanical forces generated by cells and tissues play a crucia...
Source: Annual Review of Cell and Developmental Biology - April 12, 2024 Category: Cytology Authors: Hong Huang Shaorong Gao Min Bao Source Type: research

Thymic Mimetic Cells: Ontogeny as Immunology
Annu Rev Cell Dev Biol. 2024 Apr 12. doi: 10.1146/annurev-cellbio-112122-023316. Online ahead of print.ABSTRACTMedullary thymic epithelial cells (mTECs) generate immunological self-tolerance by ectopically expressing peripheral-tissue antigens (PTAs) within the thymus to preview the peripheral self to maturing T cells. Recent work, drawing inspiration from old histological observations, has shown that subtypes of mTECs, collectively termed mimetic cells, co-opt developmental programs from throughout the organism to express biologically coherent groups of PTAs. Here, we review key aspects of mimetic cells, especially as the...
Source: Annual Review of Cell and Developmental Biology - April 12, 2024 Category: Cytology Authors: Daniel A Michelson Diane Mathis Source Type: research