Deep phenotyping of pubertal development in Norwegian children: the Bergen Growth Study 2
CONCLUSIONS: Ultrasound-based assessments of puberty provided novel references for breast developmental stages and enabled the measurement of testicular volume on a continuous scale. Endocrine z-scores allowed for an intuitive interpretation of changing hormonal levels during puberty on a quantitative scale, which, in turn, provides opportunities for further analysis of pubertal development using machine-learning approaches.PMID:37358552 | DOI:10.1080/03014460.2023.2174272 (Source: Annals of Human Biology)
Source: Annals of Human Biology - June 26, 2023 Category: Biology Authors: Petur B Juliusson Ingvild S Bruserud Ninnie Helen Bakken Oehme Andre Madsen Ingvild H Forthun Melissa Balthasar Karen Rosendahl Kristin Viste Astanand Jugessur Lawrence M Schell Robert Bjerknes Mathieu Roelants Source Type: research
Age at menarche and chemical exposure: per- and polyfluoroalkyl substances (PFAS), dichloro-diphenyl-trichloroethane (DDT), dichloro-diphenyl-dichloroethylene (DDE), and polychlorinated biphenyls (PCBs)
CONCLUSION: The absence of consistent evidence from multiple reports of earlier age at menarche suggests that these toxicants may not be responsible for accelerated sexual maturation in girls. However, human populations naturally vary in the variety and levels of exposure, making the comparison of studies difficult. Further, studies vary in methodology, complicating aggregation of results and generalisations.PMID:37357949 | DOI:10.1080/03014460.2023.2221039 (Source: Annals of Human Biology)
Source: Annals of Human Biology - June 26, 2023 Category: Biology Authors: Lawrence M Schell Casey N West Source Type: research
Does stunting still matter in high-income countries?
Ann Hum Biol. 2023 Feb;50(1):267-273. doi: 10.1080/03014460.2023.2216022.NO ABSTRACTPMID:37358011 | DOI:10.1080/03014460.2023.2216022 (Source: Annals of Human Biology)
Source: Annals of Human Biology - June 26, 2023 Category: Biology Authors: Joseph Freer Joanna Orr Robert Walton Helen L Storr Leo Dunkel Andrew J Prendergast Source Type: research
Deep phenotyping of pubertal development in Norwegian children: the Bergen Growth Study 2
CONCLUSIONS: Ultrasound-based assessments of puberty provided novel references for breast developmental stages and enabled the measurement of testicular volume on a continuous scale. Endocrine z-scores allowed for an intuitive interpretation of changing hormonal levels during puberty on a quantitative scale, which, in turn, provides opportunities for further analysis of pubertal development using machine-learning approaches.PMID:37358552 | DOI:10.1080/03014460.2023.2174272 (Source: Annals of Human Biology)
Source: Annals of Human Biology - June 26, 2023 Category: Biology Authors: Petur B Juliusson Ingvild S Bruserud Ninnie Helen Bakken Oehme Andre Madsen Ingvild H Forthun Melissa Balthasar Karen Rosendahl Kristin Viste Astanand Jugessur Lawrence M Schell Robert Bjerknes Mathieu Roelants Source Type: research
From growth charts to growth status: how concepts of optimal growth and tempo influence the interpretation of growth measurements
Ann Hum Biol. 2023 Feb;50(1):236-246. doi: 10.1080/03014460.2023.2189751.ABSTRACTGrowth measurements are largely uninterpretable without comparison to a growth chart. Consequently, the characteristics of a growth chart become an integral component of the interpretation of growth measurements. The concepts of optimal growth and tempo are well recognised by auxologists, yet their implications for interpretation of growth measurements remain problematic. This narrative review discusses the concept of optimal growth and how it serves as a guiding principle in the development and use of growth charts. The challenges of operatio...
Source: Annals of Human Biology - June 22, 2023 Category: Biology Authors: Babette S Zemel Source Type: research
Human height: a model common complex trait
CONCLUSIONS: Given the similarity of height to other complex traits, the saturation of GWAS's ability to discover additional height-associated variants signals potential limitations to the omnigenic model of complex-phenotype inheritance, indicating the likely future power of polygenic scores and risk scores, and highlights the increasing need for large-scale variant-to-gene mapping efforts.PMID:37343163 | DOI:10.1080/03014460.2023.2215546 (Source: Annals of Human Biology)
Source: Annals of Human Biology - June 21, 2023 Category: Biology Authors: Mitchell Conery Struan F A Grant Source Type: research
The problem of latent class trajectory analysis in child growth and obesity research
Ann Hum Biol. 2023 Feb;50(1):1-3. doi: 10.1080/03014460.2023.2189750.NO ABSTRACTPMID:37335012 | DOI:10.1080/03014460.2023.2189750 (Source: Annals of Human Biology)
Source: Annals of Human Biology - June 19, 2023 Category: Biology Authors: William Johnson Source Type: research
Lower educational level remains associated with lower body height among Austrian conscripts born from 1961 through 2002
Ann Hum Biol. 2023 Feb;50(1):219-222. doi: 10.1080/03014460.2023.2216472.ABSTRACTGrowth patterns and final body height are influenced by genetic and socio-environmental factors. A major impact of education on growth has been documented. Body height increases with an increasing educational level.The present study focuses on the association patterns between body height and educational level among 1,734,569 Austrian male conscripts aged 17 to <19 born between 1961 and 2002. Four levels of education were classified to examine their association with body height. Over 42 years, the percentage of conscripts at the lowest educa...
Source: Annals of Human Biology - June 8, 2023 Category: Biology Authors: Thomas Waldh ör Sylvia Kirchengast Alfred Juan Lin Yang Source Type: research
