Deciphering congenital heart defects, facial dysmorphism and intellectual developmental disorder (CHDFIDD) associated with constitutional CDK13 pathogenic variants - case report and literature review
Ann Agric Environ Med. 2024 Mar 25;31(1):147-150. doi: 10.26444/aaem/175610. Epub 2023 Dec 7.ABSTRACTThere are 21 human cyclin-dependent kinases which are involved in regulation of the cell cycle, transcription, RNA splicing, apoptosis and neurogenesis. Five of them: CDK4, CDK5, CDK6, CDK10 and CDK13 are associated with human phenotypes. To date, only 62 patients have been presented with mutated CDK13 gene. Those patients had developmental delay, dysmorphic facial features, feeding difficulties, different structural heart and brain defects. 36 of them had missense mutation affecting the protein kinase domain of CDK13. Our ...
Source: Annals of Agricultural and Environmental Medicine : AAEM - March 29, 2024 Category: Environmental Health Authors: Katarzyna Wojciechowska Micha ł Kwaśny Aleksandra Pietrzyk Monika Lejman Source Type: research

Iron deficiency, iron deficiency anaemia and anaemia of inflammation - an overview
Ann Agric Environ Med. 2024 Mar 25;31(1):151-157. doi: 10.26444/aaem/171121. Epub 2023 Oct 17.ABSTRACTIron is an essential trace element for various cellular proteins and for biological processes in all cells. Severe iron deficiency (ID) impairs haem synthesis, reduces erythropoiesis and causes iron deficiency anaemia (IDA). Iron restriction in anaemia of inflammation is mainly due to retention of iron in macrophages. This condition is known as 'functional iron deficiency'. A review of studies performed in Europe shows that the prevalence of ID and IDA in young children varies by region. It is more common in eastern than w...
Source: Annals of Agricultural and Environmental Medicine : AAEM - March 29, 2024 Category: Environmental Health Authors: Beata Kulik-Rechberger Magdalena Dubel Source Type: research

Relationship between periodontal diseases and non-specific inflammatory bowel diseases - an  overview. Part I
Ann Agric Environ Med. 2024 Mar 25;31(1):1-7. doi: 10.26444/aaem/185764. Epub 2024 Mar 21.ABSTRACTINTRODUCTION AND OBJECTIVE: An increasing number of studies indicate that the oral cavity and gastrointestinal tract are interconnected and that there is a potential causal link between non-specific inflammatory bowel diseases (IBD) and oral diseases. Therefore, following the example of the brain-gut axis, the concept of the gum-gut axis has now been put forward. The aim of the review is to assess the literature confirming the existence of the recently proposed gum-gut axis and the resulting relationships between non-specific ...
Source: Annals of Agricultural and Environmental Medicine : AAEM - March 29, 2024 Category: Environmental Health Authors: Ma łgorzata Goździewska Aleksandra Łyszczarz Monika Kaczoruk Emilia Kolarzyk Source Type: research

Prevalence of < em > Bacillus cereus < /em > in food products in Poland
CONCLUSIONS: This study provides useful information regarding the contamination of RTE products with the B. cereus group, which may have implications for food safety.PMID:38549471 | DOI:10.26444/aaem/168580 (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - March 29, 2024 Category: Environmental Health Authors: Joanna Kowalska Elzbieta Ma ćkiw Dorota Korsak Jacek Postupolski Source Type: research

Relationship between concentration of air pollutants and frequency of hospitalisations due to respiratory diseases
CONCLUSIONS: The results indicate that air pollution can be a significant modifiable risk factor for exacerbations of respiratory diseases and therefore its avoidance plays an important role in primary prevention.PMID:38549472 | DOI:10.26444/aaem/169486 (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - March 29, 2024 Category: Environmental Health Authors: Anna Grzywa-Celi ńska Adam Krusi ński Katarzyna Dos Santos Szewczyk Ewa Kurys-Denis Janusz Milanowski Source Type: research

Comparison of the method of quantitative determination of < em > Legionella pneumophila < /em > acc. to PN-EN ISO 11731:2017 with the Legiolert ™/Quanti-Tray® (IDEXX)
CONCLUSIONS: The study confirmed that the Legiolert™ test is specific and easy to use, and may constitute an alternative to standardized procedures used in the quantification of L. pneumophila in water.PMID:38549473 | DOI:10.26444/aaem/173402 (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - March 29, 2024 Category: Environmental Health Authors: Renata Matuszewska Izabela Orych Marta Bartosik Source Type: research

Occurrence of < em > Dermacentor reticulatus < /em > in  central-southern Poland, and potential threats to human and animal health
CONCLUSIONS: The results expand the available data on the spread of the ornate dog tick and indicate that, since 2010, this tick species and Rickettsia raoultii transmitted by this tick species have probably been present in this area, which has a strongly transformed agricultural structure and and had previously been regarded as a D. reticulatus-free zone. The presence of the ornate dog tick in urban and suburban habitats in central-southern Poland poses new threats to the health of companion animals and humans associated with the transmission of pathogens by this species.PMID:38549474 | DOI:10.26444/aaem/178401 (Source: A...
Source: Annals of Agricultural and Environmental Medicine : AAEM - March 29, 2024 Category: Environmental Health Authors: Alicja Buczek Weronika Buczek Maciej Rudek Marek Asman Magdalena Świsłocka Katarzyna Bartosik Source Type: research

2,4-dinitrophenol enhances cisplatin and etoposide cytotoxic activity on prostate cancer cell line
CONCLUSIONS: The enhanced cytotoxic effect of chemotherapeutics by 2,4-DNP may be the result of disturbed redox balance, reduced ability of cells to repair DNA, and the oxidative metabolic phenotype of prostate cancer cells.PMID:38549475 | DOI:10.26444/aaem/174919 (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - March 29, 2024 Category: Environmental Health Authors: Grzegorz Adamczuk Ewelina Humeniuk Kamila Adamczuk Aneta Grabarska Barbara Madej-Czerwonka Mariola Michalczuk Agnieszka Korga-Plewko Jaros ław Dudka Source Type: research

Evidence for external beam radiotherapy in mediastinal Hodgkin and non-Hodgkin lymphoma - systematic review
Ann Agric Environ Med. 2024 Mar 25;31(1):47-56. doi: 10.26444/aaem/168272. Epub 2023 Jun 26.ABSTRACTINTRODUCTION AND OBJECTIVE: Proton beam therapy (PBT) provides the opportunity for a more localized delivery of high energy protons and may reduce the damage to healthy tissues and vital organs. The aim of this review was to assess the effects of proton therapy for patients diagnosed with Hodgkin or non-Hodgkin lymphoma treated with mediastinal irradiation.REVIEW METHODS: A systematic search of EMBASE, MEDLINE via OVID and Cochrane Library was conducted in May 2022 according to PRISMA guidelines to identify relevant data on ...
Source: Annals of Agricultural and Environmental Medicine : AAEM - March 29, 2024 Category: Environmental Health Authors: Malwina Kowalska Ewelina Sitarz-Kilian Klaudia Jaros Magdalena Koperny Pawe ł Moćko Jacek Siwiec Pawe ł Kawalec Source Type: research

Healthy and sustainable school meals - proposal for a new quality index SMI-LE
CONCLUSIONS: A novel tool to has been provided for measuring the quality of school meals that addresses health and sustainability issues. It responds to the need for new indices that would consider changes in dietary guidelines and increasing knowledge about the impact of food systems on the environment.PMID:38549477 | DOI:10.26444/aaem/171610 (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - March 29, 2024 Category: Environmental Health Authors: Marta Jeruszka-Bielak Magdalena G órnicka Source Type: research

A national registry-based study on uptake of the first dose of MMR vaccine in 380 administrative regions in Poland, 2013-2016-2020
CONCLUSIONS: This study revealed that in 61% of administrative regions in Poland, the MMR vaccine uptake was below the herd immunity level. Regional differences in the MMR vaccine uptake were observed. A significant decrease in MMR vaccine uptake between 2013 - 2020 poses a risk of measles outbreaks.PMID:38549478 | DOI:10.26444/aaem/172887 (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - March 29, 2024 Category: Environmental Health Authors: Piotr Samel-Kowalik Mateusz Jankowski Aneta Tomaszewska Karolina Sobeczek Kamil Rakocy Boles ław Krzysztof Samoliński Mariusz Gujski Jaros ław Pinkas Anastasiia Vatsenko Filip Raciborski Source Type: research

Geriatric Depression Scale - 30 assessments: face-to-face or telephone interviews for older people - a randomized crossover study
CONCLUSIONS: Findings of the study showed that the GDS-30 questionnaire had a high compliance in both face-to-face and telephone surveys.PMID:38549479 | DOI:10.26444/aaem/173530 (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - March 29, 2024 Category: Environmental Health Authors: Bernard Soza ński Agnieszka Beata Ćwirlej-Sozańska Agnieszka Wi śniowska-Szurlej Anna Wilmowska-Pietruszy ńska Renata Spalek Alessandro de Sire Source Type: research

Changes in eating behaviours and physical activity among primary schoolchildren aged 7-12 during the pandemic in the light of qualitative and quantitative research - Junior-Edu- Żywienie (JEŻ) Project
CONCLUSIONS: There is a need to develop post-pandemic support strategies addressed to both schoolchildren and their parents regarding adequate eating behaviours and physical activity.PMID:38549480 | DOI:10.26444/aaem/175537 (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - March 29, 2024 Category: Environmental Health Authors: Krystyna Gutkowska Ewa Czarniecka-Skubina Jadwiga Hamu łka Marta Jeruszka-Bielak Source Type: research

Association between cyberchondria and the use of complementary and alternative medicine (CAM) - a cross-sectional study
CONCLUSIONS: The research results indicate that there is a link between cyberchondria and the use of CAM. However, since some components of the CSS-PL scale and self-rated health were not associated with more frequent use of CAM, it is likely that these results may not be fully reliable. The association between cyberchondria and CAM use should be investigated in further studies using comprehensive medical interviews.PMID:38549481 | DOI:10.26444/aaem/178503 (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - March 29, 2024 Category: Environmental Health Authors: Aneta Brygida J ędrzejewska Grzegorz J ózef Nowicki Ewa Rudnicka-Dro żak Lech Panasiuk Barbara Janina Ślusarska Source Type: research

Efficacy of photodynamic therapy using ALAHCl in gel with a lipid nanoemulsion and MALHCl in cream in superficial basal cell carcinoma
CONCLUSIONS: Both formulations - ALA-HCl in gel and MAL-HCl in cream - were highly effective photosensitisers for PDT. The advantage of ALA-HCl in a gel formulation with a lipid nanoemulsion was faster skin healing, resulting in better cosmetic results.PMID:38549482 | DOI:10.26444/aaem/183059 (Source: Annals of Agricultural and Environmental Medicine : AAEM)
Source: Annals of Agricultural and Environmental Medicine : AAEM - March 29, 2024 Category: Environmental Health Authors: Paulina Szczepanik-Ku łak Joanna Bartosi ńska Dorota Kowalczuk Agnieszka Gerkowicz Iwona Bojar Miros ław Kwaśny Dorota Krasowska Source Type: research