Association between interleukin-12 +1188A/C polymorphism and the risk of tuberculosis: a meta-analysis
Conclusion: The present findings indicated that IL-12 +1188A/C polymorphism was not related to the risk of TB.Keywords: IL-12; tuberculosis; meta-analysis. (Source: African Health Sciences)
Source: African Health Sciences - July 13, 2023 Category: African Health Authors: Pengcheng Wang, Jiadan Liao Source Type: research
Frequency of latent tuberculosis in patients receiving Anti-TNF-Alpha therapy
Conclusion: The incidence of tuberculosis development in patients treated with anti TNF- α was found to be higher than the general population. In our country, where tuberculosis is still prevalent, patients receiving Anti TNF-α treatment (especially infliximab) should be carefully questioned and examined about tuberculosis.Keywords: Anti-TNF-alpha; tuberculosis; tuberculin skin test. (Source: African Health Sciences)
Source: African Health Sciences - July 13, 2023 Category: African Health Authors: İpek Coşkunol, Onur Turan, Aysegul Baysak, Dilek Solmaz, Gerçek Can Source Type: research
Health-related quality of life among children/adolescents living with HIV/AIDS in Lagos State, Nigeria
This study compares the characteristics of children with HRQL classified as good, intermediate, and poor quality of life. The children and adolescents that have a good health-related quality of life had a mean rank of 75.5, intermediate, 27.0 while children and adolescents with poor HRQL had a mean rank of 8.5. The health -related quality of life differs significantly across the demographic characteristics. However, tertiary education does not differ significantly on HRQL. The Kruskal-Wallis ’s chi-squared was 76.95 with two degrees of freedom and p-value< 2.2e-16. The p-value< 0.05 indicates sufficient evidence th...
Source: African Health Sciences - July 13, 2023 Category: African Health Authors: Kazeem Osuolale, Abideen Salako, Adesola Musa, Oluwatosin Odubela, Fatimah Adepoju-Olajuwon, Agatha David, Tiitilola Gbaja-Biamila, Oliver Ezechi, Babatunde Salako Source Type: research
Biological parameters determining the effectiveness of monitoring of HIV / AIDS infected patients in Morocco
Conclusion: In our study, we showed a therapeutic failure rate of 18.2% in HIV-infected patients under treatment in Marrakech region. These failures were mainly related to poor adherence and low CD4+ rates at the initiation of treatment. We concluded that immunological monitoring alone is insufficient to predict virological suppression and therapeutic success. Consequently, we recommend the HIV plasma viral load test be accessible as a routine exam.Keywords: HIV; viral load; CD4; therapeutic failure; antiretroviral treatment; Morocco. (Source: African Health Sciences)
Source: African Health Sciences - July 13, 2023 Category: African Health Authors: Mohamed Echchakery, Ali Boumezzough, Samia Boussaa Source Type: research
Factors influencing tuberculosis preventive practices among people living with HIV/AIDS enrolled in secondary health facilities in Lagos, Nigeria
Conclusion: Over half of respondents had good tuberculosis preventive practices, influenced by their socio-demographic characteristics, knowledge and attitude towards TB infection. Preventive efforts need to be strengthened among individuals between 18-27 years of age, non-Christians and those with lower educational status.Keywords: PLHIV; TB prevention; knowledge; attitude; practice. (Source: African Health Sciences)
Source: African Health Sciences - July 13, 2023 Category: African Health Authors: Sunday Olakunle Olarewaju, Roseline Oluyemisi Akande, Charity Abu, Charles Adeyemo Source Type: research
