The Relationships among Internalized Stigma, Sense of Coherence, and Personal Recovery of Persons with Schizophrenia Living in the Community
Acta Med Okayama. 2024 Apr;78(2):171-184. doi: 10.18926/AMO/66926.ABSTRACTWe investigated (i) the relationships among internalized stigma (IS), sense of coherence (SOC), and the personal recovery (PR) of persons with schizophrenia living in the community, and (ii) how to improve the support for these individuals. A questionnaire survey on IS, SOC, and PR was sent by mail to 270 persons with schizophrenia living in the community who were using psychiatric daycare services, of whom 149 responded and 140 were included in the analysis. We established a hypothetical model in which IS influences PR, and SOC influences IS and PR,...
Source: Acta Med Okayama - April 30, 2024 Category: Universities & Medical Training Authors: Aya Kuramoto Shinya Saito Kumi Watanabe Source Type: research
Reduced Immunogenicity of COVID-19 Vaccine in Obese Patients with Type 2 Diabetes: A Cross-Sectional Study
Acta Med Okayama. 2024 Apr;78(2):185-191. doi: 10.18926/AMO/66927.ABSTRACTThe global pandemic of coronavirus infection 2019 (COVID-19) was an unprecedented public health emergency. Several clinical studies reported that heart disease, lung disease, diabetes, hypertension, dyslipidemia, and obesity are critical risk factors for increased severity of and hospitalization for COVID-19. This is largely because patients with these underlying medical conditions can show poor immune responses to the COVID-19 vaccinations. Diabetes is one of the underlying conditions most highly associated with COVID-19 susceptibility and is consid...
Source: Acta Med Okayama - April 30, 2024 Category: Universities & Medical Training Authors: Hiroko Takahashi Jun Eguchi Mayu Watanabe Masanori Nakayama Jun Wada Source Type: research
Laparoscopic Resection Combined with a Transsacral Approach for a Recurrent Tailgut Cyst with a Refractory Fistula
We describe a case in which the combination of laparoscopic and transsacral approaches was effective for resecting a recurrent refractory fistula after incomplete resection of a tail gut cyst.PMID:38688837 | DOI:10.18926/AMO/66928 (Source: Acta Med Okayama)
Source: Acta Med Okayama - April 30, 2024 Category: Universities & Medical Training Authors: Hajime Kashima Fuminori Teraishi Yuki Matsumi Hiroshi Shimamura Toshiyoshi Fujiwara Source Type: research
Perineal Squamous Cell Carcinoma Arising in an Epidermal Cyst
Acta Med Okayama. 2024 Apr;78(2):197-200. doi: 10.18926/AMO/66930.ABSTRACTA 90-year-old Japanese woman who had been aware of a subcutaneous mass on the right perineal region for 5 years was referred to our hospital for further examination and treatment because of the rapid growth of the mass and bleeding that began 3 months earlier. A biopsy of the mass revealed a diagnosis of well-differentiated squamous cell carcinoma. On preoperative examination, the tumor was 90×40 mm in size and was suspected to have partially invaded the levator ani muscle and external sphincter. Since a preoperative cardiac evaluation indicated sev...
Source: Acta Med Okayama - April 30, 2024 Category: Universities & Medical Training Authors: Fuminori Teraishi Yuki Matsumi Kota Tachibana Toshiyuki Watanabe Toshiyoshi Fujiwara Source Type: research
A Case of Gallbladder Cancer with Trousseau Syndrome Successfully Treated Using Radical Resection
We describe the first case of a successfully treated gallbladder adenocarcinoma accompanied by Trousseau syndrome. A 66-year-old woman presented with right hemiplegia. Magnetic resonance imaging identified multiple cerebral infarctions. Her serum carbohydrate antigen 19-9 and D-dimer levels were markedly elevated, and a gallbladder tumor was detected via abdominal computed tomography. Venous ultrasonography of the lower limbs revealed a deep venous thrombus in the right peroneal vein. These findings suggested that the brain infarctions were likely caused by Trousseau syndrome associated with her gallbladder cancer. Radical...
Source: Acta Med Okayama - April 30, 2024 Category: Universities & Medical Training Authors: Akari Masunaga Motoyasu Tabuchi Shinya Sakamoto Rika Yoshimatsu Manabu Matsumoto Jun Iwata Takehiro Okabayashi Source Type: research
Role of Macrophages in Liver Fibrosis
Acta Med Okayama. 2024 Feb;78(1):1-8. doi: 10.18926/AMO/66664.ABSTRACTLiver fibrosis, which ultimately leads to liver cirrhosis and hepatocellular carcinoma, is a major health burden worldwide. The progression of liver fibrosis is the result of the wound-healing response of liver to repeated injury. Hepatic macrophages are cells with high heterogeneity and plasticity and include tissue-resident macrophages termed Kupffer cells, and recruited macrophages derived from circulating monocytes, spleen and peritoneal cavity. Studies have shown that hepatic macrophages play roles in the initiation and progression of liver fibrosis...
Source: Acta Med Okayama - February 29, 2024 Category: Universities & Medical Training Authors: Cuiming Sun Akihiro Matsukawa Source Type: research
Prostate Biopsy May Not Be Indicated Early after Bacillus Calmette Gu érin Treatment
Acta Med Okayama. 2024 Feb;78(1):9-13. doi: 10.18926/AMO/66665.ABSTRACTBacillus Calmette-Guérin (BCG) treatment for non-muscle-invasive bladder cancer frequently causes an intraprostatic BCG granuloma. We investigated the optimal timing for a prostate biopsy after BCG treatment by retrospectively analyzing the cases of 22 patients with non-muscle-invasive bladder cancer who underwent a prostate biopsy after BCG treatment at our institute (2013-2017). Biopsies were indicated for a rising prostate-specific antigen (PSA) level, positive digital rectal examination findings, or the appearance of de novo low apparent diffusion ...
Source: Acta Med Okayama - February 29, 2024 Category: Universities & Medical Training Authors: Naoki Akagi Akihiro Kanematsu Koji Shigesaka Kimihiro Shimatani Shingo Yamamoto Source Type: research
Lung Oligometastasis of Breast Cancer: Prospective Cohort Study of Treatment Strategies (SBP-06)
Acta Med Okayama. 2024 Feb;78(1):15-20. doi: 10.18926/AMO/66666.ABSTRACTWhile local treatment of metastases is considered to be unrelated to prognosis, previous studies have suggested that local treatment of isolated lung metastases may have positive prognostic impact. We designed this prospective cohort study to investigate the clinical situation and its outcomes. We enrolled patients with fewer than 3 lung nodules suspected of being oligometastases after curative breast cancer surgery. Treatments, including local and systemic therapy, were selected by the physician and patient in consultation. The primary outcome was ove...
Source: Acta Med Okayama - February 29, 2024 Category: Universities & Medical Training Authors: Reina Maeda Tadahiko Shien Mina Takahashi Kengo Kawada Yukiko Kajiwara Shinichiro Kubo Daisuke Takabatake Shoichiro Ohtani Kinya Matsuoka Hajime Hikino Yutaka Ogasawara Naruto Taira Shozo Osumi Masahiko Ikeda Hiroyoshi Doihara Source Type: research
Assessing the Frequency and Effectiveness of Various Arthroscopic Treatments in the Management of Symptomatic Isolated Medial Meniscus Injuries Including Medial Meniscus Posterior Root Tear: A Retrospective Observational Cohort Study
Acta Med Okayama. 2024 Feb;78(1):21-27. doi: 10.18926/AMO/66667.ABSTRACTThe use of various strategies for arthroscopic meniscal repairs to save the meniscus and prevent the progression of knee osteoarthritis has gradually increased. We investigated the frequency of various arthroscopic treatments and the short-term clinical outcomes of symptomatic isolated medial meniscus (MM) injuries. This retrospective observational study included 193 patients (197 knees) who underwent arthroscopic meniscal treatment for isolated MM injuries between January 2016 and April 2019. Arthroscopic meniscal repairs were divided into two groups:...
Source: Acta Med Okayama - February 29, 2024 Category: Universities & Medical Training Authors: Masanori Tamura Takayuki Furumatsu Yusuke Yokoyama Keisuke Kintaka Naohiro Higashihara Koki Kawada Toshifumi Ozaki Source Type: research
Regression of Necrotic Lesions after Methotrexate Withdrawal in Patients with Methotrexate-Associated Lymphoproliferative Disorders: A Retrospective CT Study
Acta Med Okayama. 2024 Feb;78(1):29-36. doi: 10.18926/AMO/66668.ABSTRACTThis retrospective study investigated whether necrotic lesions detected on a computed tomography (CT) scan are more regressive than non-necrotic lesions after methotrexate withdrawal in patients pathologically diagnosed with methotrexate-associated lymphoproliferative disorders (MTX-LPD). In total, 89 lesions extracted from 24 patients on CT scans were included in the analysis. All patients had been evaluated for the presence of necrosis within lesions via CT scan upon first suspicion of MTX-LPD (baseline CT scan). The percentage lesion size reduction ...
Source: Acta Med Okayama - February 29, 2024 Category: Universities & Medical Training Authors: Takahiro Kitayama Takashi Tanaka Yuichiro Kanie Yohei Marukawa Katsuhide Kojima Takehiro Tanaka Soshi Takao Takao Hiraki Source Type: research
Is Proximal Triangular Fixation Better than the Conventional Method in Adult Spinal Deformity Surgery?
Acta Med Okayama. 2024 Feb;78(1):37-46. doi: 10.18926/AMO/66669.ABSTRACTIn adult spinal deformity (ASD) surgery, one of the key factors working to prevent proximal junctional kyphosis is the proximal anchor. The aim of this study was to compare clinical and radiographic outcomes of triangular fixation with conventional fixation as proximal anchoring techniques in ASD surgery. We retrospectively evaluated 54 patients who underwent corrective spinal fusion for ASD. Fourteen patients underwent proximal triangular fixation (Group T; average 74.6 years), and 40 patients underwent the conventional method (Group C; average 70.5 y...
Source: Acta Med Okayama - February 29, 2024 Category: Universities & Medical Training Authors: Masato Tanaka Umesh Meena Takuya Taoka Yoshihiro Fujiwara Daiichiro Yokomizo Santosh Kumar Bashyal Naveen Sake Shinya Arataki Source Type: research
Long-Term Follow-up Data of a Multi-Institutional Phase-2 Study of S-1/oxaliplatin and Bevacizumab Therapy in Patients with Advanced Colorectal Cancer: The HiSCO-02 Study
In conclusion, we report here the final prognostic update of the Phase II clinical trial examining the efficacy of SOX plus bevacizumab therapy, the results of which confirm the clinical efficacy of this regimen.PMID:38419314 | DOI:10.18926/AMO/66670 (Source: Acta Med Okayama)
Source: Acta Med Okayama - February 29, 2024 Category: Universities & Medical Training Authors: Manabu Shimomura Katsunori Shinozaki Takuya Yano Shintaro Akabane Hideki Ohdan Hiroshima Surgical study group of Clinical Oncology (HiSCO) Source Type: research
Quantitative Assessment of the Heat Transfer Capacity of Ice Bags and their Cooling Effects on the Skin Surface and Core Temperature
This study quantifies heat energy transfer capacity of ice bags and evaluates their cooling effects on body temperature. Forty-eight healthy adults in their 20s were recruited. An ice bag wrapped in two layers of dry towel was applied to the forehead, neck, or palm of each participant for 10 min. The skin surface temperature, heat flow, and core temperature were recorded during the cooling and non-cooling periods, with energy transfer calculated by integrating heat flow over time. Over the non-cooling period, 31.4-53.6 kJ·m-2 of energy was dissipated over 10 min, whereas during the cooling period, the range increased to 1...
Source: Acta Med Okayama - February 29, 2024 Category: Universities & Medical Training Authors: Yukiko Ichikawa Tetsuya Ogino Source Type: research
Significance of Continuous Low-Dose Lenvatinib for the Treating of the Patients with Unresectable Thyroid Carcinoma
Acta Med Okayama. 2024 Feb;78(1):63-70. doi: 10.18926/AMO/66672.ABSTRACTThe tyrosine kinase inhibitor lenvatinib has been confirmed as an effective treatment option for patients with unresectable thyroid carcinoma. We conducted a retrospective analysis of the significance of the effect of continued lenvatinib treatment for the longest duration possible at a reasonable daily dose and with a minimum discontinuation period in 42 patients with unresectable thyroid carcinoma treated with lenvatinib between 2015 and 2020. A Cox proportional hazard model-based analysis revealed that the overall survival of the patients treated wi...
Source: Acta Med Okayama - February 29, 2024 Category: Universities & Medical Training Authors: Daizo Murakami Kohei Nishimoto Soshi Takao Satoru Miyamaru Tomoka Kadowaki Haruki Saito Hiroki Takeda Momoko Ise Koichi Suyama Yorihisa Orita Source Type: research
High Fracture Rate of AVANTA Silicone Implant Following Arthroplasty of the Thumb MCP Joint of Rheumatoid Arthritis Patients with Boutonniere Deformities
This study involved 36 thumbs of 33 RA patients with a mean follow-up period of 5.1 years (range, 2.0-13.3). Postoperatively, the mean extension was significantly increased and the mean flexion was significantly decreased (p<0.001, p<0.001, respectively), resulting in the mean arc of range of motion (ROM) shifting in the direction of extension after surgery. Implant fracture was observed in 10 thumbs (28%), and 4 of these (11%) underwent revision surgery. The survivorship with implant fracture and revision surgery as endpoints were 73.4% and 91.8% at 5 years, respectively. The preoperative arc of ROM and the postoper...
Source: Acta Med Okayama - February 29, 2024 Category: Universities & Medical Training Authors: Daisuke Kaneda Keiichiro Nishida Yoshihisa Nasu Ryuichi Nakahara Ryozo Harada Yoshifumi Hotta Shuichi Naniwa Toshifumi Ozaki Source Type: research
