Ectopic Breast Cancer Arising within an Axillary Lymph Node
We report our experience with the diagnosis and treatment of an ectopic breast cancer arising within an axillary lymph node. The patient was a 65-year-old woman diagnosed breast cancer and axillary lymph node metastasis. We performed a partial mastectomy and axillary lymph node dissection. Postoperative pathology revealed no malignant lesions in the breast; however, a nodule in one of axillary lymph nodes had mixed benign and malignant components, leading to a diagnosis of invasive ductal carcinoma derived from ectopic mammary tissue. This case represents a very rare form of breast cancer, and the malignancy was difficult ...
Source: Acta Med Okayama - February 29, 2024 Category: Universities & Medical Training Authors: Kei Toshima Tadahiko Shien Midori Filiz Nishimura Yoko Suzuki Shogo Nakamoto Maya Uno Ryo Yoshioka Takahiro Tsukioki Yuko Takahashi Takayuki Iwamoto Tsuguo Iwatani Hiroyuki Yanai Source Type: research
Role of Macrophages in Liver Fibrosis
Acta Med Okayama. 2024 Feb;78(1):1-8. doi: 10.18926/AMO/66664.ABSTRACTLiver fibrosis, which ultimately leads to liver cirrhosis and hepatocellular carcinoma, is a major health burden worldwide. The progression of liver fibrosis is the result of the wound-healing response of liver to repeated injury. Hepatic macrophages are cells with high heterogeneity and plasticity and include tissue-resident macrophages termed Kupffer cells, and recruited macrophages derived from circulating monocytes, spleen and peritoneal cavity. Studies have shown that hepatic macrophages play roles in the initiation and progression of liver fibrosis...
Source: Acta Med Okayama - February 29, 2024 Category: Universities & Medical Training Authors: Cuiming Sun Akihiro Matsukawa Source Type: research
Prostate Biopsy May Not Be Indicated Early after Bacillus Calmette Gu érin Treatment
Acta Med Okayama. 2024 Feb;78(1):9-13. doi: 10.18926/AMO/66665.ABSTRACTBacillus Calmette-Guérin (BCG) treatment for non-muscle-invasive bladder cancer frequently causes an intraprostatic BCG granuloma. We investigated the optimal timing for a prostate biopsy after BCG treatment by retrospectively analyzing the cases of 22 patients with non-muscle-invasive bladder cancer who underwent a prostate biopsy after BCG treatment at our institute (2013-2017). Biopsies were indicated for a rising prostate-specific antigen (PSA) level, positive digital rectal examination findings, or the appearance of de novo low apparent diffusion ...
Source: Acta Med Okayama - February 29, 2024 Category: Universities & Medical Training Authors: Naoki Akagi Akihiro Kanematsu Koji Shigesaka Kimihiro Shimatani Shingo Yamamoto Source Type: research
Lung Oligometastasis of Breast Cancer: Prospective Cohort Study of Treatment Strategies (SBP-06)
Acta Med Okayama. 2024 Feb;78(1):15-20. doi: 10.18926/AMO/66666.ABSTRACTWhile local treatment of metastases is considered to be unrelated to prognosis, previous studies have suggested that local treatment of isolated lung metastases may have positive prognostic impact. We designed this prospective cohort study to investigate the clinical situation and its outcomes. We enrolled patients with fewer than 3 lung nodules suspected of being oligometastases after curative breast cancer surgery. Treatments, including local and systemic therapy, were selected by the physician and patient in consultation. The primary outcome was ove...
Source: Acta Med Okayama - February 29, 2024 Category: Universities & Medical Training Authors: Reina Maeda Tadahiko Shien Mina Takahashi Kengo Kawada Yukiko Kajiwara Shinichiro Kubo Daisuke Takabatake Shoichiro Ohtani Kinya Matsuoka Hajime Hikino Yutaka Ogasawara Naruto Taira Shozo Osumi Masahiko Ikeda Hiroyoshi Doihara Source Type: research
Assessing the Frequency and Effectiveness of Various Arthroscopic Treatments in the Management of Symptomatic Isolated Medial Meniscus Injuries Including Medial Meniscus Posterior Root Tear: A Retrospective Observational Cohort Study
Acta Med Okayama. 2024 Feb;78(1):21-27. doi: 10.18926/AMO/66667.ABSTRACTThe use of various strategies for arthroscopic meniscal repairs to save the meniscus and prevent the progression of knee osteoarthritis has gradually increased. We investigated the frequency of various arthroscopic treatments and the short-term clinical outcomes of symptomatic isolated medial meniscus (MM) injuries. This retrospective observational study included 193 patients (197 knees) who underwent arthroscopic meniscal treatment for isolated MM injuries between January 2016 and April 2019. Arthroscopic meniscal repairs were divided into two groups:...
Source: Acta Med Okayama - February 29, 2024 Category: Universities & Medical Training Authors: Masanori Tamura Takayuki Furumatsu Yusuke Yokoyama Keisuke Kintaka Naohiro Higashihara Koki Kawada Toshifumi Ozaki Source Type: research
