IMRT Versus 3DCRT for Locally Advanced Rectal Cancer, Prospective Phase II Study.
Conditions: Rectal Cancer; Radiotherapy; Toxicity Due to Radiotherapy Interventions: Radiation: Intensive Modulated Radiation Therapy; Radiation: 3-Dimension Conformal Radiation Therapy Sponsors: Rabin Medical Center Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 7, 2023 Category: Research Source Type: clinical trials

Nasopharyngeal Carcinoma Treated With Reduced Volume Intensity Modulated Radiation Therapy:10-Year Outcome and Late Toxicity, Quality of Life
Conditions: Nasopharyngeal Carcinoma Sponsors: Fujian Cancer Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 17, 2023 Category: Research Source Type: clinical trials

New-mode Clinical Target Volume Delineation of Nasopharyngeal Carcinoma
Conditions: Nasopharyngeal Carcinoma by AJCC V8 Stage Interventions: Radiation: New-mode reduce-volume target IMRT Sponsors: Fujian Cancer Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 23, 2023 Category: Research Source Type: clinical trials

Reduced-dose RT With/Without CCT Versus Standard CCRT for High-risk LANPC Who Achieved CR Post Induction Chemotherapy
Conditions: Nasopharyngeal Carcinoma; De-escalation Therapy Interventions: Drug: Cisplatin-based induction chemotherapy; Drug: Full course of PD-1/PD-L1 blockades; Radiation: Reduced-dose IMRT; Radiation: Standard-dose IMRT; Drug: Concurrent Chemotherapy Sponsors: Sun Yat-sen University; First Affiliated Hospital, Sun Yat-Sen University; Affiliated Cancer Hospital& Institute of Guangzhou Medical University; Guangdong Provincial People ' s Hospital; Second Affiliated Hospital, Sun Yat-Sen University; The fifth Affiliated Hospital of Guangzhou Medcial University; Zhongshan People ' s Hospital, Guangdong, China; Hunan Cancer ...
Source: ClinicalTrials.gov - October 20, 2023 Category: Research Source Type: clinical trials

Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck Cancer
Conditions: Head and Neck Squamous Cell Carcinoma; Hypopharyngeal Squamous Cell Carcinoma; Laryngeal Squamous Cell Carcinoma; Oral Cavity Squamous Cell Carcinoma; Oropharyngeal Squamous Cell Carcinoma; Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8; Stage III Hypopharyngeal Carcinoma AJCC v8; Stage III Laryngeal Cancer AJCC v8; Stage III Lip and Oral Cavity Cancer AJCC v8; Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8; Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8; Stage IV Hypopharyngeal Carcinoma AJCC v8; Stage IV Laryngeal Cancer AJCC v8; Stage IV Lip and Or...
Source: ClinicalTrials.gov - October 16, 2023 Category: Research Source Type: clinical trials

Phase II Randomized Study of Hypofractionated Versus Conventional Radiotherapy
Conditions: Laryngeal Carcinoma Interventions: Radiation: LT-SABR; Radiation: IMRT Sponsors: University of Texas Southwestern Medical Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 12, 2023 Category: Research Source Type: clinical trials

Phase 1b Safety Study of Xevinapant, Weekly Cisplatin, and RT in Participants With Unresected LA SCCHN (HyperlynX)
Condition:   Head and Neck Cancer Interventions:   Drug: Xevinapant;   Drug: Cisplatin;   Radiation: intensity-modulated radiation therapy (IMRT) Sponsors:   EMD Serono Research & Development Institute, Inc.;   Merck KGaA, Darmstadt, Germany Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 27, 2023 Category: Research Source Type: clinical trials

Phase 1b Safety Study of Xevinapant, Weekly Cisplatin, and RT in Participants With Unresected LA SCCHN (HyperlynX)
Conditions: Head and Neck Cancer Interventions: Drug: Xevinapant; Drug: Cisplatin; Radiation: intensity-modulated radiation therapy (IMRT) Sponsors: EMD Serono Research& Development Institute, Inc.; Merck KGaA, Darmstadt, Germany Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 27, 2023 Category: Research Source Type: clinical trials

SAHARA-04 : Adaptive Radiotherapy in Hypersensitive Patients and High Locoregional Risk Breast Cancer With ETHOS Technology
Condition:   Breast Cancer Interventions:   Radiation: Treatment ETHOS radiotherapy;   Radiation: Conventional IMRT Sponsor:   Institut du Cancer de Montpellier - Val d'Aurelle Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 25, 2023 Category: Research Source Type: clinical trials

SAHARA-04 : Adaptive Radiotherapy in Hypersensitive Patients and High Locoregional Risk Breast Cancer With ETHOS Technology
Conditions: Breast Cancer Interventions: Radiation: Treatment ETHOS radiotherapy; Radiation: Conventional IMRT Sponsors: Institut du Cancer de Montpellier - Val d ' Aurelle Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 25, 2023 Category: Research Source Type: clinical trials

Dose-Painted Intensity Modulated Radiotherapy Pancreas (DP-IMRT Pancreas)
Condition:   Pancreatic Adenocarcinoma Intervention:   Radiation: Dose-Painted Intensity Modulated Radiotherapy Sponsor:   Cancer Trials Ireland Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 6, 2023 Category: Research Source Type: clinical trials