Pilot Randomized trial of Fibrinogen in Trauma Haemorrhage (PRooF-iTH): study protocol for a randomized controlled trial
Discussion
Patients considered to be included in the trial will temporarily have a compromised consciousness because of the acute, critical bleeding related to trauma, so scientific guardians will co-sign the informed consent form. Next of kin and the patients’ general practitioner or the patients will co-sign as soon as possible.
This trial will test whether immediate pre-emptive fibrinogen concentrate administered to adult trauma patients as first-line treatment of trauma haemorrhage will increase the clot strength as evaluated by thrombelastography, transfusion requirements ...
Source: Trials - July 18, 2016 Category: Research Source Type: clinical trials
Human Fibrinogen Concentrate in Pediatric Cardiac Surgery
Conditions: Hypofibrinogenemia; Afibrinogenemia; Bleeding DisordersInterventions: Drug: RiaStAP; Drug: SalineSponsor: Nicklaus Children's Hospital f/k/a Miami Children's HospitalNot yet recruiting - verified June 2016 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 30, 2016 Category: Research Source Type: clinical trials
