Study of Imdusiran (AB-729) in Combination With Intermittent Dosing of Durvalumab in Subjects With Chronic HBV Infection
Conditions: Hepatitis B, Chronic Interventions: Drug: Imdusiran; Drug: Durvalumab Sponsors: Arbutus Biopharma Corporation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 7, 2024 Category: Research Source Type: clinical trials

GUM Remote Testing v4.0
Conditions: HIV Infections; Syphilis Infection; Hepatitis B and Hepatitis C Interventions: Diagnostic Test: HIV diagnostic testing Sponsors: Royal Devon and Exeter NHS Foundation Trust Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 6, 2024 Category: Research Source Type: clinical trials

Regulation of Intestinal Flora by Compound Probiotics in Patients With Chronic Hepatitis B
Conditions: Chronic Hepatitis B Interventions: Dietary Supplement: Probiotic Sponsors: Wecare Probiotics Co., Ltd. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 24, 2024 Category: Research Source Type: clinical trials

Clinical Trial for Non-inferiority and Safety of Tenofovir Alafenamide and Tenofovir Disoproxil Fumarate in Patients With Hematologic Malignancies Who Require Prophylactic Hepatitis B Antiviral Treatment
Conditions: Patients With Malignant Blood Disease Requiring Hepatitis B Antiviral Medication Interventions: Drug: Vemlidy; Drug: Virreal Sponsors: Yonsei University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 24, 2024 Category: Research Source Type: clinical trials

Vaccinal Effect of HBsAg Monoclonal Ab VIR-3434 in Chronic Hepatitis B Infection [VISION]
Conditions: Hepatitis B, Chronic Interventions: Drug: VIR-3434 Sponsors: University Health Network, Toronto Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 22, 2024 Category: Research Source Type: clinical trials

Immunogenicity of the Inactivated EV71 Vaccine Combined With Hepatitis B and Group A Meningococcal Vaccine
Conditions: Hand, Foot and Mouth Disease Interventions: Biological: Enterovirus Type 71 Vaccine, inactivated ( Human Diploid Cell ); Biological: Recombinant Hepatitis B Vaccine; Biological: Group A meningococcal polysaccharide vaccine Sponsors: Jiangsu Province Centers for Disease Control and Prevention; Institute of Medical Biology, Chinese Academy of Medical Sciences Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2024 Category: Research Source Type: clinical trials

Tacrolimus versus mycophenolate for AutoImmune hepatitis patients with incompLete response On first-line therapy (TAILOR study): a study protocol for a phase III, open-label, multicentre, randomised controlled trial
DiscussionThis is the first randomised controlled trial comparing two second-line therapies for AIH. Currently, second-line treatment is based on retrospective cohort studies. The rarity of AIH is the main issue in clinical research for alternative treatment options. The results of this trial can be implemented in existing international clinical guidelines.Trial registrationClinicalTrials.govNCT05221411. Retrospectively registered on 3 February 2022; EudraCT number 2021 –003420-33. Prospectively registered on 16 June 2021. (Source: Trials)
Source: Trials - January 17, 2024 Category: Research Source Type: clinical trials

Hepatitis C Virus Self-testing (HCVST) in Sexual and Gender Minorities in Rio de Janeiro
Conditions: Hepatitis C Interventions: Diagnostic Test: Hepatitis C virus self-test (oral fluid HCVST); Diagnostic Test: Hepatitis C virus self-test (blood-based HCVST) Sponsors: Oswaldo Cruz Foundation; World Health Organization; UNITAID Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 12, 2024 Category: Research Source Type: clinical trials

Improving Perinatal Outcomes Among Kenyan Pregnant Women With an Integrated STI Testing Model
Conditions: Hiv; Sexually Transmitted Infections (Not HIV or Hepatitis) Interventions: Diagnostic Test: Xpert ® CT/NG and TV testing Sponsors: University of Washington; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 12, 2024 Category: Research Source Type: clinical trials

The Effect of Gentle Human Touch and Kangaroo Care on Pain and Crying Physiological Parameters During Hepatitis-B Vaccination in a Newborn
Conditions: Pain Interventions: Other: Gentle Human Touch (GHT); Other: Kangaroo Care; Other: Lactation Sponsors: Kirsehir Ahi Evran Universitesi Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 9, 2024 Category: Research Source Type: clinical trials

Development and Validation of Models to Predict Functional Cure in Patients With CHB After Peg-IFN Based Therapy
Conditions: Hepatitis B, Chronic Interventions: Drug: Peginterferon- α; Nucleoside analogs Sponsors: Qilu Hospital of Shandong University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 9, 2024 Category: Research Source Type: clinical trials

Entecavir versus tenofovir for prevention of hepatitis B virus-associated hepatocellular carcinoma after curative resection: study protocol for a randomized, open-label trial
This study is a randomized, open-label trial. A total of 240 participants will be randomized 1:1 into groups receiving TDF or entecavir monotherapy. The two groups will be compared in terms of recurrence-free and overall survival at 1, 3, and 5  years after surgery; adverse events; virological response; rate of alanine transaminase normalization; and seroreactivity at 24 and 48 weeks after surgery.DiscussionThis study will compare long-term survival between patients with HBV-associated HCC who receive TDF or entecavir monotherapy. Numerous outcomes related to prognosis will be analyzed and compared in this study.Trial re...
Source: Trials - January 5, 2024 Category: Research Source Type: clinical trials

Hepatitis A Virus Induced Acute Acalculous Cholecystitis Diagnosed Postoperatively: Case Report
Conditions: Acute Acalculous Cholecystitis Interventions: Other: Laparoscopic cholecystectomy for hepatitis A induced acute acalculous cholecystitis Sponsors: University of Balamand Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 4, 2024 Category: Research Source Type: clinical trials

Characteristics and Risk Factors for Invasive Fungal Infection With Acute-on-chronic Hepatitis B Liver Failure
Conditions: Acute-on-chronic Hepatitis B Liver Failure Sponsors: Qilu Hospital of Shandong University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 4, 2024 Category: Research Source Type: clinical trials

Persistence of Hepatitis A Antibody in Healthy Adults ~32 Years Post Vaccination.
Conditions: Hepatitis A Interventions: Biological: Hepatitis A Vaccine Sponsors: Best Healthcare Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 28, 2023 Category: Research Source Type: clinical trials