Forteo Plus Prolia Builds Bone (CME/CE)
(MedPage Today) -- Treatment with a combination of teriparatide (Forteo) plus denosumab (Prolia) led to greater increases in bone mineral density in postmenopausal women with osteoporosis than either agent alone, a randomized trial showed. (Source: MedPage Today Endocrinology)
Source: MedPage Today Endocrinology - May 14, 2013 Category: Endocrinology Source Type: news
Insulet To Develop New Version Of The OmniPod Insulin Pump For Use With Humulin R U-500 Concentrated Insulin For People With Type 2 Diabetes
Insulet Corporation (NASDAQ:PODD), the leader intubeless insulin pumptechnology with its OmniPod® Insulin Management System, today announced it has entered into an agreement with Eli Lilly and Company in which Insulet will develop a new version of the OmniPod insulin pump specifically designed to deliver Humulin® R U-500 insulin, (regular U-500 [Concentrated] insulin human injection, USP [rDNA origin]), a concentrated form of insulin used by people with highly insulin resistant type 2 diabetes. (Source: Pharmaceutical Online News)
Source: Pharmaceutical Online News - May 3, 2013 Category: Pharmaceuticals Source Type: news
What Causes Hypercalcemia?
Discussion
Calcium homeostasis is regulated by mechanisms involving the absorption from the gastrointestinal tract, bone deposition and resorption, and renal excretion. To review Vitamin D homeostasis click here.
Serum calcium is found in three forms: free (47%), protein bound (43%) and diffusable calcium complexes (10%). The protein binding proteins are albumin (80%) and globulin (20%). The free calcium is the most important biologically. Acidosis also increases free calcium and alkalosis decreases free calcium.
Problems associated with hypercalcemia include nausea, emesis, abdominal pain, constipation, polyuria, dehydra...
Source: PediatricEducation.org - March 25, 2013 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news
