In situ gelling nanosuspension as an advanced platform for fluticasone propionate nasal delivery
Eur J Pharm Biopharm. 2022 Apr 27:S0939-6411(22)00081-9. doi: 10.1016/j.ejpb.2022.04.009. Online ahead of print.ABSTRACTIn this work we present the development of in situ gelling nanosuspension as advanced form for fluticasone propionate nasal delivery. Drug nanocrystals were prepared by wet milling technique. Incorporation of drug nanocrystals into polymeric in situ gelling system with pectin and sodium hyaluronate as constitutive polymers was fine-tuned attaining appropriate formulation surface tension, viscosity and gelling ability. Drug nanonisation improved the release profile and enhanced formulation mucoadhesive pro...
Source: European Journal of Pharmaceutics and Biopharmaceutics - April 30, 2022 Category: Drugs & Pharmacology Authors: Laura Ni žić Nodilo Mirna Perku šić Ivo Ugrina Drago Špoljarić Cvijeta Jakobu šić Brala Daniela Amid žić Klarić Jasmina Lovri ć Vesna Sar šon Ma ša Safundžić Kučuk Dijana Zadravec Livije Kalogjera Ivan Pepi ć Anita Hafner Source Type: research
In situ gelling nanosuspension as an advanced platform for fluticasone propionate nasal delivery
Eur J Pharm Biopharm. 2022 Apr 27:S0939-6411(22)00081-9. doi: 10.1016/j.ejpb.2022.04.009. Online ahead of print.ABSTRACTIn this work we present the development of in situ gelling nanosuspension as advanced form for fluticasone propionate nasal delivery. Drug nanocrystals were prepared by wet milling technique. Incorporation of drug nanocrystals into polymeric in situ gelling system with pectin and sodium hyaluronate as constitutive polymers was fine-tuned attaining appropriate formulation surface tension, viscosity and gelling ability. Drug nanonisation improved the release profile and enhanced formulation mucoadhesive pro...
Source: European Journal of Pharmaceutics and Biopharmaceutics - April 30, 2022 Category: Drugs & Pharmacology Authors: Laura Ni žić Nodilo Mirna Perku šić Ivo Ugrina Drago Špoljarić Cvijeta Jakobu šić Brala Daniela Amid žić Klarić Jasmina Lovri ć Vesna Sar šon Ma ša Safundžić Kučuk Dijana Zadravec Livije Kalogjera Ivan Pepi ć Anita Hafner Source Type: research
In situ gelling nanosuspension as an advanced platform for fluticasone propionate nasal delivery
Eur J Pharm Biopharm. 2022 Apr 27:S0939-6411(22)00081-9. doi: 10.1016/j.ejpb.2022.04.009. Online ahead of print.ABSTRACTIn this work we present the development of in situ gelling nanosuspension as advanced form for fluticasone propionate nasal delivery. Drug nanocrystals were prepared by wet milling technique. Incorporation of drug nanocrystals into polymeric in situ gelling system with pectin and sodium hyaluronate as constitutive polymers was fine-tuned attaining appropriate formulation surface tension, viscosity and gelling ability. Drug nanonisation improved the release profile and enhanced formulation mucoadhesive pro...
Source: European Journal of Pharmaceutics and Biopharmaceutics - April 30, 2022 Category: Drugs & Pharmacology Authors: Laura Ni žić Nodilo Mirna Perku šić Ivo Ugrina Drago Špoljarić Cvijeta Jakobu šić Brala Daniela Amid žić Klarić Jasmina Lovri ć Vesna Sar šon Ma ša Safundžić Kučuk Dijana Zadravec Livije Kalogjera Ivan Pepi ć Anita Hafner Source Type: research
In situ gelling nanosuspension as an advanced platform for fluticasone propionate nasal delivery
Eur J Pharm Biopharm. 2022 Apr 27:S0939-6411(22)00081-9. doi: 10.1016/j.ejpb.2022.04.009. Online ahead of print.ABSTRACTIn this work we present the development of in situ gelling nanosuspension as advanced form for fluticasone propionate nasal delivery. Drug nanocrystals were prepared by wet milling technique. Incorporation of drug nanocrystals into polymeric in situ gelling system with pectin and sodium hyaluronate as constitutive polymers was fine-tuned attaining appropriate formulation surface tension, viscosity and gelling ability. Drug nanonisation improved the release profile and enhanced formulation mucoadhesive pro...
Source: European Journal of Pharmaceutics and Biopharmaceutics - April 30, 2022 Category: Drugs & Pharmacology Authors: Laura Ni žić Nodilo Mirna Perku šić Ivo Ugrina Drago Špoljarić Cvijeta Jakobu šić Brala Daniela Amid žić Klarić Jasmina Lovri ć Vesna Sar šon Ma ša Safundžić Kučuk Dijana Zadravec Livije Kalogjera Ivan Pepi ć Anita Hafner Source Type: research
In situ gelling nanosuspension as an advanced platform for fluticasone propionate nasal delivery
Eur J Pharm Biopharm. 2022 Apr 27:S0939-6411(22)00081-9. doi: 10.1016/j.ejpb.2022.04.009. Online ahead of print.ABSTRACTIn this work we present the development of in situ gelling nanosuspension as advanced form for fluticasone propionate nasal delivery. Drug nanocrystals were prepared by wet milling technique. Incorporation of drug nanocrystals into polymeric in situ gelling system with pectin and sodium hyaluronate as constitutive polymers was fine-tuned attaining appropriate formulation surface tension, viscosity and gelling ability. Drug nanonisation improved the release profile and enhanced formulation mucoadhesive pro...
Source: European Journal of Pharmaceutics and Biopharmaceutics - April 30, 2022 Category: Drugs & Pharmacology Authors: Laura Ni žić Nodilo Mirna Perku šić Ivo Ugrina Drago Špoljarić Cvijeta Jakobu šić Brala Daniela Amid žić Klarić Jasmina Lovri ć Vesna Sar šon Ma ša Safundžić Kučuk Dijana Zadravec Livije Kalogjera Ivan Pepi ć Anita Hafner Source Type: research
In situ gelling nanosuspension as an advanced platform for fluticasone propionate nasal delivery
Eur J Pharm Biopharm. 2022 Apr 27:S0939-6411(22)00081-9. doi: 10.1016/j.ejpb.2022.04.009. Online ahead of print.ABSTRACTIn this work we present the development of in situ gelling nanosuspension as advanced form for fluticasone propionate nasal delivery. Drug nanocrystals were prepared by wet milling technique. Incorporation of drug nanocrystals into polymeric in situ gelling system with pectin and sodium hyaluronate as constitutive polymers was fine-tuned attaining appropriate formulation surface tension, viscosity and gelling ability. Drug nanonisation improved the release profile and enhanced formulation mucoadhesive pro...
Source: European Journal of Pharmaceutics and Biopharmaceutics - April 30, 2022 Category: Drugs & Pharmacology Authors: Laura Ni žić Nodilo Mirna Perku šić Ivo Ugrina Drago Špoljarić Cvijeta Jakobu šić Brala Daniela Amid žić Klarić Jasmina Lovri ć Vesna Sar šon Ma ša Safundžić Kučuk Dijana Zadravec Livije Kalogjera Ivan Pepi ć Anita Hafner Source Type: research
