Non-invasive prenatal testing for the diagnosis of congenital abnormalities: Insights from a large multicenter study in southern China
Braz J Med Biol Res. 2023 Jun 26;56:e12506. doi: 10.1590/1414-431X2023e12506. eCollection 2023.ABSTRACTAlthough non-invasive prenatal testing (NIPT) is widely used to detect fetal abnormalities, the results of NIPT vary by population, and data for the screening efficiency of NIPT positive predictive value (PPV) from different populations is limited. Herein, we retrospectively analyzed the NIPT results in a large multicenter study involving 52,855 pregnant women. Depending on gestational age, amniotic fluid or umbilical cord blood was extracted for karyotype and/or chromosome microarray analysis (CMA) in NIPT-positive patie...
Source: Brazilian Journal of Medical and Biological Research - June 28, 2023 Category: Research Authors: Meiying Cai Na Lin Xuemei Chen Ying Li Min Lin Xianguo Fu Hailong Huang Shuqiong He Liangpu Xu Source Type: research
Non-invasive prenatal testing for the diagnosis of congenital abnormalities: Insights from a large multicenter study in southern China
Braz J Med Biol Res. 2023 Jun 26;56:e12506. doi: 10.1590/1414-431X2023e12506. eCollection 2023.ABSTRACTAlthough non-invasive prenatal testing (NIPT) is widely used to detect fetal abnormalities, the results of NIPT vary by population, and data for the screening efficiency of NIPT positive predictive value (PPV) from different populations is limited. Herein, we retrospectively analyzed the NIPT results in a large multicenter study involving 52,855 pregnant women. Depending on gestational age, amniotic fluid or umbilical cord blood was extracted for karyotype and/or chromosome microarray analysis (CMA) in NIPT-positive patie...
Source: Braz J Med Biol Res - June 28, 2023 Category: Research Authors: Meiying Cai Na Lin Xuemei Chen Ying Li Min Lin Xianguo Fu Hailong Huang Shuqiong He Liangpu Xu Source Type: research
Non-invasive prenatal testing for the diagnosis of congenital abnormalities: Insights from a large multicenter study in southern China
Braz J Med Biol Res. 2023 Jun 26;56:e12506. doi: 10.1590/1414-431X2023e12506. eCollection 2023.ABSTRACTAlthough non-invasive prenatal testing (NIPT) is widely used to detect fetal abnormalities, the results of NIPT vary by population, and data for the screening efficiency of NIPT positive predictive value (PPV) from different populations is limited. Herein, we retrospectively analyzed the NIPT results in a large multicenter study involving 52,855 pregnant women. Depending on gestational age, amniotic fluid or umbilical cord blood was extracted for karyotype and/or chromosome microarray analysis (CMA) in NIPT-positive patie...
Source: Brazilian Journal of Medical and Biological Research - June 28, 2023 Category: Research Authors: Meiying Cai Na Lin Xuemei Chen Ying Li Min Lin Xianguo Fu Hailong Huang Shuqiong He Liangpu Xu Source Type: research
Non-invasive prenatal testing for the diagnosis of congenital abnormalities: Insights from a large multicenter study in southern China
Braz J Med Biol Res. 2023 Jun 26;56:e12506. doi: 10.1590/1414-431X2023e12506. eCollection 2023.ABSTRACTAlthough non-invasive prenatal testing (NIPT) is widely used to detect fetal abnormalities, the results of NIPT vary by population, and data for the screening efficiency of NIPT positive predictive value (PPV) from different populations is limited. Herein, we retrospectively analyzed the NIPT results in a large multicenter study involving 52,855 pregnant women. Depending on gestational age, amniotic fluid or umbilical cord blood was extracted for karyotype and/or chromosome microarray analysis (CMA) in NIPT-positive patie...
Source: Braz J Med Biol Res - June 28, 2023 Category: Research Authors: Meiying Cai Na Lin Xuemei Chen Ying Li Min Lin Xianguo Fu Hailong Huang Shuqiong He Liangpu Xu Source Type: research
Non-invasive prenatal testing for the diagnosis of congenital abnormalities: Insights from a large multicenter study in southern China
Braz J Med Biol Res. 2023 Jun 26;56:e12506. doi: 10.1590/1414-431X2023e12506. eCollection 2023.ABSTRACTAlthough non-invasive prenatal testing (NIPT) is widely used to detect fetal abnormalities, the results of NIPT vary by population, and data for the screening efficiency of NIPT positive predictive value (PPV) from different populations is limited. Herein, we retrospectively analyzed the NIPT results in a large multicenter study involving 52,855 pregnant women. Depending on gestational age, amniotic fluid or umbilical cord blood was extracted for karyotype and/or chromosome microarray analysis (CMA) in NIPT-positive patie...
Source: Brazilian Journal of Medical and Biological Research - June 28, 2023 Category: Research Authors: Meiying Cai Na Lin Xuemei Chen Ying Li Min Lin Xianguo Fu Hailong Huang Shuqiong He Liangpu Xu Source Type: research
Non-invasive prenatal testing for the diagnosis of congenital abnormalities: Insights from a large multicenter study in southern China
Braz J Med Biol Res. 2023 Jun 26;56:e12506. doi: 10.1590/1414-431X2023e12506. eCollection 2023.ABSTRACTAlthough non-invasive prenatal testing (NIPT) is widely used to detect fetal abnormalities, the results of NIPT vary by population, and data for the screening efficiency of NIPT positive predictive value (PPV) from different populations is limited. Herein, we retrospectively analyzed the NIPT results in a large multicenter study involving 52,855 pregnant women. Depending on gestational age, amniotic fluid or umbilical cord blood was extracted for karyotype and/or chromosome microarray analysis (CMA) in NIPT-positive patie...
Source: Braz J Med Biol Res - June 28, 2023 Category: Research Authors: Meiying Cai Na Lin Xuemei Chen Ying Li Min Lin Xianguo Fu Hailong Huang Shuqiong He Liangpu Xu Source Type: research
Non-invasive prenatal testing for the diagnosis of congenital abnormalities: Insights from a large multicenter study in southern China
Braz J Med Biol Res. 2023 Jun 26;56:e12506. doi: 10.1590/1414-431X2023e12506. eCollection 2023.ABSTRACTAlthough non-invasive prenatal testing (NIPT) is widely used to detect fetal abnormalities, the results of NIPT vary by population, and data for the screening efficiency of NIPT positive predictive value (PPV) from different populations is limited. Herein, we retrospectively analyzed the NIPT results in a large multicenter study involving 52,855 pregnant women. Depending on gestational age, amniotic fluid or umbilical cord blood was extracted for karyotype and/or chromosome microarray analysis (CMA) in NIPT-positive patie...
Source: Brazilian Journal of Medical and Biological Research - June 28, 2023 Category: Research Authors: Meiying Cai Na Lin Xuemei Chen Ying Li Min Lin Xianguo Fu Hailong Huang Shuqiong He Liangpu Xu Source Type: research
