Drugs & Pharmacology Clinical Trials This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Pharmacist-guided pre-emptive pharmacogenetic testing in antidepressant therapy (PrePGx): study protocol for an open-label, randomized controlled trial
This study is an open-label, randomized controlled trial conducted in two study centers in Switzerland: (1) the Psychiatric Clinic of Solothurn and (2) the Private Clinic Wyss in M ünchenbuchsee. Adult inpatients diagnosed with a unipolar moderate or severe depressive episode are recruited at clinic admission and are included in the study. If the adjustment to a new antidepressant pharmacotherapy is necessary, the participants are randomized to either Arm A (intervention grou p) or Arm B (control group). If no new antidepressant pharmacotherapy is introduced the participants will be followed up in an observational arm. Th...
Source: Trials - December 14, 2021 Category: Research Source Type: clinical trials

A Clinical Pharmacology Trial of Brexpiprazole Long Acting Injectable (LAI) Administered as a Single Dose in Patients With Schizophrenia
Condition: Schizophrenia Interventions: Drug: Brexpiprazole LAI: Dose 1; Drug: Brexpiprazole LAI: Dose 2; Drug: Brexpiprazole LAI: Dose 3; Drug: Brexpiprazole LAI: Dose 4 Sponsor: Otsuka Pharmaceutical Co., Ltd. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 15, 2021 Category: Research Source Type: clinical trials

Efficacy and safety of dual intravenous artesunate plus quinine compared to intravenous artesunate for cerebral malaria in a triple blinded parallel multisite randomized controlled trial in Nigerian children: DUAL PAQ TRIAL Protocol
This study outlines a protocol to conduct a triple blinded parallel randomized controlled trial on cerebral malaria using dual intravenous medications compared to the current standard of monotherapy.MethodsThis is a parallel multi-site randomized controlled superiority triple blinded trial consisting of intravenous artesunate plus quinine and a control arm of intravenous artesunate only. Eligible and assenting children aged 6 months to 17 years will be recruited from 4 tertiary hospitals by random selection from the list of tertiary hospitals in Nigeria. Participants will be randomized and assigned in parallel into tw...
Source: Trials - October 20, 2021 Category: Research Source Type: clinical trials

Echinaforce Study to Investigate Explorative Pharmacology and Effectiveness to Prevent From Enveloped Virus Infections
Conditions: Respiratory Tract Infections; Common Cold Intervention: Drug: Echinaforce Chewable tablets Sponsors: A. Vogel AG; CONVEX CRO; d.s.h. statistical services GmbH; MediStat Ltd.; Biodome Clinical; Bodimed; PPES lab epigenetic signaling Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - August 12, 2021 Category: Research Source Type: clinical trials