The Autoantigens and Neoantigens Function in the Etiology and Pathophysiology of Type 1 Diabetes (R01 Clinical Trial Optional)
Funding Opportunity RFA-DK-21-004 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages applications from institutions and organizations proposing original research aimed at the characterization of the function of neoepitopes and neoantigens in type 1 diabetes. This includes the function that post-translational modifications might have in the humoral and cell mediated autoimmune responses and overall in the etiology and pathophysiology of type 1 diabetes. Proposals that include the discovery of neoantigens or neoepitopes are within the scope of this solicitation, but should ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 17, 2021 Category: Research Source Type: funding
HEAL Initiative: Analgesic Development Initial Translational Efforts [Small Molecules and Biologics] (U19 Clinical Trial Not Allowed)
Funding Opportunity RFA-NS-21-015 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) is part of a suite of FOAs to support the development of safe, effective, and non-addictive therapeutics to treat pain. The goal of this FOA is to support team-based research projects to develop assays, screening and early optimization work to develop a non-addictive therapeutic to treat pain. Discovery and validation of pharmacodynamic markers efficacy and pharmacokinetic/pharmacodynamic (PK/PD) studies are also responsive. The result of the project should be to advance a hit or lead to the point w...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 11, 2021 Category: Research Source Type: funding
Immune Cell Engineering For Targeted Therapy And Disease Monitoring in Type 1 Diabetes (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-DK-21-005 from the NIH Guide for Grants and Contracts. This initiative will support the engineering of immune cells to target the human pancreatic compartment to report on previously inaccessible information about diabetes initiation and progression, and to deliver environment-specific therapeutic responses to restore islet health and prevent the progression to T1D. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 19, 2021 Category: Research Source Type: funding
Maine Community Benefit Program
Grants for nonprofit organizations working to promote wellness and community health in Maine. Preference is given to projects that focus on asthma, coronary artery disease, chronic obstructive pulmonary disease, depression, diabetes, hypertension, and substance use disorder. Applications from rural and Tribal communities are encouraged. Geographic coverage: Maine -- Community Health Options (Source: Funding opportunities via the Rural Health Information Hub)
Source: Funding opportunities via the Rural Health Information Hub - February 5, 2021 Category: American Health Source Type: funding
Biomarkers for Diabetic Foot Ulcers through the Diabetic Foot Consortium (R61/R33 Clinical Trial Not Allowed)
Funding Opportunity RFA-DK-21-001 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement is to promote the development of prognostic, monitoring, and diagnostic biomarkers for diabetic foot ulcers that can be used in clinicaltrials and patient care. This initiative would support early analytical and clinical validation of biomarkers through a phased award to encourage innovative research. The initiative would leverage the resources of the Diabetic Foot Consortium to facilitate the access to well-characterized patients and high-quality human samples. The goal of this initiative ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 13, 2021 Category: Research Source Type: funding
Priority HIV/AIDS Research within the Mission of the NIDDK (R01 Clinical Trial Optional)
Funding Opportunity PAS-21-031 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) seeks to stimulate HIV/AIDS research within the mission of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) that align with the HIV/AIDS research priorities outlined by the NIH Office of AIDS Research (OAR). These priorities were most recently described in NOT-OD-20-018 UPDATE: NIH HIV/AIDS Research Priorities and Guidelines for Determining HIV/AIDS Funding. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 8, 2021 Category: Research Source Type: funding
Limited Competition: Revision to the Coordinating Center for Type 1 Diabetes TrialNet (U01 Clinical Trial Required)
Funding Opportunity RFA-DK-20-508 from the NIH Guide for Grants and Contracts. Type 1 diabetes (T1D) is a serious and burdensome chronic disease that usually onsets in childhood or early adulthood. Recent progress in clinical trials and understanding of T1D pathogenesis and mechanisms have created opportunities to delay the onset and progression of the disease. This supplement is intended to provide resources for the design and conduct of new intervention studies in individuals at early pre-clinical stages of T1D and in individuals with new-onset T1D through the T1D TrialNet network (TrialNet). This Funding Opportunity ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 7, 2021 Category: Research Source Type: funding
Pilot and Feasibility Studies to Facilitate the Use of Diabetes Self-Management Education and Support to Improve Diabetes Care (R34 Clinical Trial Required)
Funding Opportunity RFA-DK-20-032 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to test an innovative and pragmatic approach to address barriers to and facilitate greater use of diabetes self-management education and support (DSMES) by people living with diabetes mellitus. Research applications should engage key stakeholders in cultivating a practical and sustainable strategy with the potential for dissemination. The pilot trial of the proposed strategy should be designed to generate preliminary data in support of a future, full-scale trial to study broader di...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 6, 2021 Category: Research Source Type: funding
Understanding and Reducing Cardiovascular Disease in Type 1 Diabetes Mellitus (R01 Clinical Trial Optional)
Funding Opportunity RFA-HL-21-014 from the NIH Guide for Grants and Contracts. The goal of this funding opportunity is to support research that enhances the understanding of the pathophysiology and epidemiology of cardiovascular disease (CVD) among individuals with Type 1 Diabetes Mellitus (T1DM), and support the development of interventions to reduce CVD risk among these individuals. The overall goal is to develop evidence-based guidelines to prevent or reduce CVD complications of T1DM across the lifespan. This funding opportunity will support epidemiologic studies to refine risk assessment, mechanistic studies to enha...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 6, 2021 Category: Research Source Type: funding
Diabetes Research Centers (P30 Clinical Trial Optional)
Funding Opportunity RFA-DK-20-025 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications for Diabetes Research Centers that are designed to support and enhance the national research effort in diabetes, its complications, and related endocrine and metabolic diseases. Diabetes Research Centers support two primary research-related activities: Research Core services and a Pilot and Feasibility (P and F) program. All activities pursued by Diabetes Research Centers are designed to enhance the efficiency, productivity, effectiveness, and multidisciplinary nature of researc...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 19, 2020 Category: Research Source Type: funding
Understanding the Cellular and Molecular Mechanisms of Gastroparesis in Adults and Children (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-DK-20-030 from the NIH Guide for Grants and Contracts. Since its establishment in 2006, the Gastroparesis Clinical Research Consortium (GpCRC), a multi-center coalition created and funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), has made major advances to our understanding of the pathophysiology of gastroparesis (Gp) and develop an effective treatment for patients with symptomatic gastroparesis. Through the establishment of the largest gastroparesis tissue repository, combined with detailed phenotypic data, the GpCRC is ideally suited to accelerate insights...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 13, 2020 Category: Research Source Type: funding
NIDDK Education Program Grants (R25 Clinical Trial Not Allowed)
Funding Opportunity PAR-21-034 from the NIH Guide for Grants and Contracts. The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on: Courses for Skills Development Research Experiences These courses for skill development and research exper...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 19, 2020 Category: Research Source Type: funding
Limited Competition for the Continuation of the Scientific Data Research Center (SDRC) for the NIDDK Gastroparesis Consortium (U24 Clinical Trial Optional)
Funding Opportunity RFA-DK-20-505 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites an application for the Scientific Data Research Center (SDRC) of the Gastroparesis Clinical Research Consortium (GpCRC). The companion FOA, RFA-DK-20-504 will support continuation of the GpCRC Clinical Centers (CC). The Consortium forms a multi-disciplinary teams composed of members from the CCs and SDRC to undertake a comprehensive clinical, epidemiological and biological characterization of adult and children patients with GP to gain insight into the pathophysiology of GP and its sequela: ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 24, 2020 Category: Research Source Type: funding
Limited Competition for Continuation of the Integrated Islet Distribution Program (U24 Clinical Trial Not Allowed)
Funding Opportunity RFA-DK-20-509 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites one application from the Program Director(s)/Principal Investigator(s) of the current Integrated Islet Distribution Program (IIDP) to renew the program andmaintain support for its continuing mission to provide the scientific community with important islet resources for diabetes research.The IIDP facilitates the distribution of human islets to biomedical researchers byestablishing partnerships with qualified islet isolation facilities to prepare and distribute human islets. The programmanages...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 22, 2020 Category: Research Source Type: funding
Limited Competition for the Continuation of the Urinary Stone Disease Research Network (USDRN) Clinical Centers (U01 Clinical Trial Required)
Funding Opportunity RFA-DK-20-506 from the NIH Guide for Grants and Contracts. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)s Urinary Stone Disease Research Network (USDRN) is conducting a multi-center randomized clinical trial and an observational clinical study to a) provide evidence on the effects of increased fluid intake and urine output on urinary stone disease recurrence through innovative adherence strategies, b) understand and mitigate ureteral stent-associated pain and urinary symptoms, and c) collect data and biological samples for future investigations. The purpose of this Limi...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 10, 2020 Category: Research Source Type: funding
