Treating Diabetes Distress to Improve Glycemic Outcomes in Type 1 Diabetes (R01 Clinical Trial Required)
This FOA seeks applications for clinical trials testing interventions targeting diabetes distress in individuals with type 1 diabetes and/or their caregivers, with the goal of understanding whether lowering diabetes distress will improve glycemic control and quality of life. Given the clinical care recommendation that screening for diabetes distress take place in the context of medical care, applications should reflect a practical team approach to screening and treatment that could realistically occur in a clinical setting.RFA-DK-19-021 (Source: NIDDK Funding Opportunities)
Source: NIDDK Funding Opportunities - January 2, 2020 Category: Endocrinology Source Type: funding

Discovery of Early Type 1 Diabetes Disease Processes in the Human Pancreas [HIRN Consortium on Beta Cell Death and Survival (CBDS)] (U01 Clinical Trial Not Allowed)
This Funding Opportunity Announcement (FOA) requests applications to explore human pancreatic tissues for the discovery of specific signaling or processing pathways that may contribute to the asymptomatic phase of T1D, the discovery of early biomarkers of T1D pathogenesis, the development of diagnostic tools for the detection and staging of early T1D in at-risk or recently-diagnosed individuals, and/or the identification and biological validation of therapeutic targets for the development of preventative or early treatment strategies. Successful applicants will join the Consortium on Beta Cell Death and Survival (CBDS), wh...
Source: NIDDK Funding Opportunities - January 2, 2020 Category: Endocrinology Source Type: funding

Development and Integration of Novel Components for Open and Closed Loop Hormone Replacement Platforms for T1D Therapy (R01 Clinical Trial Optional)
This Funding Opportunity Announcement (FOA) encourages applications from institutions/organizations proposing original research addressing barriers that limit progress toward effective open- and closed-loop glucose control systems. Proposed research should tackle important obstacles at the level of sensing, hormone formulation and delivery, self-management decision support systems, and/or design of automated controllers/algorithms able to manage an integrated platform. This research may contribute to development of affordable and user friendly technologies to improve glucose control in patients with type 1 diabetes.Guiller...
Source: NIDDK Funding Opportunities - January 2, 2020 Category: Endocrinology Source Type: funding

Notice of Special Interest (NOSI): Addressing Health Disparities in NIDDK Diseases
The overall objective of this NOSI is to understand and mitigate health disparities in the development, diagnosis, and treatment of diseases of high priority to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). It is recognized that both biologic and non-biologic factors may be operating in these underserved populations.Robert Rivers, Ph.D. | NOT-DK-20-003 (Source: NIDDK Funding Opportunities)
Source: NIDDK Funding Opportunities - December 16, 2019 Category: Endocrinology Source Type: funding

Limited Competition: NIDDK Program Projects (P01 Clinical Trial Optional)
Funding Opportunity PAR-20-075 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites submission of investigator-initiated Research Program Project Grant (P01) renewal (Type 2) applications. The proposed programs should address scientific areas relevant to the NIDDK mission including diabetes, selected endocrine and metabolic diseases, obesity, digestive diseases and nutrition, and kidney, urologic and hematologic diseases, as well as new approaches to prevent, treat and cure these diseases, including clinical research. A description of NIDDK scientific program areas can be foun...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 11, 2019 Category: Research Source Type: funding

Limited Competition: NIDDK Program Projects (P01 Clinical Trial Optional)
This Funding Opportunity Announcement (FOA) invites submission of investigator-initiated Research Program Project Grant (P01) renewal (Type 2) applications. The proposed programs should address scientific areas relevant to the NIDDK mission including diabetes, selected endocrine and metabolic diseases, obesity, digestive diseases and nutrition, and kidney, urologic and hematologic diseases, as well as new approaches to prevent, treat and cure these diseases, including clinical research. A description of NIDDK scientific program areas can be found at https://www.niddk.nih.gov/about-niddk/research-areas.National Institute of...
Source: NIDDK Funding Opportunities - December 11, 2019 Category: Endocrinology Source Type: funding

Support for Small Business Innovation Research (SBIR) to Development and Testing of New Technologies and Bioengineering Solutions for the Advancement of Cell Replacement Therapies for Type 1 Diabetes (R43/R44 Clinical Trial Not Allowed)
Funding Opportunity RFA-DK-19-028 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites Small Business Innovation Research (SBIR) grant applications for funding to perform research leading to the development of novel and supportive technologies for the improvement of cell replacement interventions using novel methods, biomaterials and devices for type 1 diabetes (T1D) treatment. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 10, 2019 Category: Research Source Type: funding

Support for Small Business Innovation Research (SBIR) to Development and Testing of New Technologies and Bioengineering Solutions for the Advancement of Cell Replacement Therapies for Type 1 Diabetes (R43/R44 Clinical Trial Not Allowed)
This Funding Opportunity Announcement (FOA) invites Small Business Innovation Research (SBIR) grant applications for funding to perform research leading to the development of novel and supportive technologies for the improvement of cell replacement interventions using novel methods, biomaterials and devices for type 1 diabetes (T1D) treatment.RFA-DK-19-028 (Source: NIDDK Funding Opportunities)
Source: NIDDK Funding Opportunities - December 10, 2019 Category: Endocrinology Source Type: funding

Type 1 Diabetes in Acute Pancreatitis Consortium - Clinical Centers (T1DAPC-CCs) (U01 Clinical Trial Optional)
Funding Opportunity RFA-DK-19-022 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) solicits U01 applications for the establishment of a clinical consortium, composed of one Data Coordinating Center (DCC) and up to 10 Clinical Centers (CC), to conduct studies on diabetes mellitus, with an emphasis on Type 1 diabetes (T1D), that occurs after or as a consequence of one or more episodes of acute pancreatitis. The Consortium will form multi-disciplinary teams composed of members from the CCs and DCC to undertake a prospective longitudinal observational study of the occurrence of diabet...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 9, 2019 Category: Research Source Type: funding

Type 1 Diabetes in Acute Pancreatitis Consortium - Data Coordinating Center (T1DAPC-DCC) (U01 Clinical Trial Optional)
Funding Opportunity RFA-DK-19-023 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) solicits U01 applications for the establishment of a clinical consortium, the Type 1 Diabetes in Acute Pancreatitis Consortium (T1DAPC), composed of one Data Coordinating Center (DCC) and up to 10 Clinical Centers (CC), to conduct studies on Type 1 diabetes mellitus (T1D) that occurs after or as a consequence of one or more episodes of acute pancreatitis. Applications for the Clinical Centers (CC) are submitted in response to a separate FOA: RFA-DK-19-022: Type 1 Diabetes in Acute Pancreatitis Conso...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 9, 2019 Category: Research Source Type: funding

Type 1 Diabetes in Acute Pancreatitis Consortium - Clinical Centers (T1DAPC-CCs) (U01 Clinical Trial Optional)
This Funding Opportunity Announcement (FOA) solicits U01 applications for the establishment of a clinical consortium, composed of one Data Coordinating Center (DCC) and up to 10 Clinical Centers (CC), to conduct studies on diabetes mellitus, with an emphasis on Type 1 diabetes (T1D), that occurs after or as a consequence of one or more episodes of acute pancreatitis. The Consortium will form multi-disciplinary teams composed of members from the CCs and DCC to undertake a prospective longitudinal observational study of the occurrence of diabetes that occurs during an acute pancreatitis episode or subsequently, with an empha...
Source: NIDDK Funding Opportunities - December 9, 2019 Category: Endocrinology Source Type: funding

Type 1 Diabetes in Acute Pancreatitis Consortium - Data Coordinating Center (T1DAPC-DCC) (U01 Clinical Trial Optional)
This Funding Opportunity Announcement (FOA) solicits U01 applications for the establishment of a clinical consortium, the Type 1 Diabetes in Acute Pancreatitis Consortium (T1DAPC), composed of one Data Coordinating Center (DCC) and up to 10 Clinical Centers (CC), to conduct studies on Type 1 diabetes mellitus (T1D) that occurs after or as a consequence of one or more episodes of acute pancreatitis. Applications for the Clinical Centers (CC) are submitted in response to a separate FOA: RFA-DK-19-022: Type 1 Diabetes in Acute Pancreatitis Consortium Clinical Centers (T1DAPC-CC) (U01). The applicant for the Data Coordinating ...
Source: NIDDK Funding Opportunities - December 9, 2019 Category: Endocrinology Source Type: funding

Clinical Trials to Test Artificial Pancreas Device Systems in Populations Challenging to Manage Type 1 Diabetes (T1D) (U01 Clinical Trial Required)
Funding Opportunity RFA-DK-19-036 from the NIH Guide for Grants and Contracts. This FOA will support the conduct of clinical trials designed to test the clinical safety and efficacy of artificial pancreas (AP) device systems with the objective of improving glycemic control, reducing acute complications and improving quality of life in people with difficult to control T1D when using standard of care therapies. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 4, 2019 Category: Research Source Type: funding

Clinical Trials to Test Artificial Pancreas Device Systems in Populations Challenging to Manage Type 1 Diabetes (T1D) (U01 Clinical Trial Required)
This FOA will support the conduct of clinical trials designed to test the clinical safety and efficacy of artificial pancreas (AP) device systems with the objective of improving glycemic control, reducing acute complications and improving quality of life in people with difficult to control T1D when using standard of care therapies.RFA-DK-19-036 (Source: NIDDK Funding Opportunities)
Source: NIDDK Funding Opportunities - December 4, 2019 Category: Endocrinology Source Type: funding

Expanding NIH ’s Definition of Socio-Economic Disadvantaged to be More Inclusive and Diversify the Workforce
An extensive literature demonstrates that socioeconomic status is one of the strongest predictors of health, on par with typical risk markers like smoking, physical inactivity, hypertension, and diabetes.  An intriguing graphic shows life expectancy according to stops on the London subway system – as described in a news story, “if you travel eastbound between Lancaster Gate and Mile End – 20 minutes on the Central line – life expectancy decreases by 12 years.”  This association of strong links between socioeconomic status and health is remarkably reproducible – including on subway maps of the ...
Source: NIH Extramural Nexus - November 26, 2019 Category: Research Authors: Mike Lauer Tags: blog Open Mike Biomedical Workforce Diversity Source Type: funding