Improving mental health in chronic care in general practice: study protocol for a cluster-randomised controlled trial of the Healthy Mind intervention
This study protocol describes a randomised controlled trial of the Healthy Mind intervention, a general practice-based intervention offering PST to patients with type 2 diabetes and/or ischaemic heart disease and poor mental well-being.MethodsA stepped-wedge cluster-randomised controlled trial with 1-year follow-up will be conducted in Danish general practice. At the annual chronic care consultation, patients with type 2 diabetes and/or chronic ischaemic heart disease will be screened for poor mental well-being. Patients in the control group will be offered usual care while patients in the intervention group will be offere...
Source: Trials - April 23, 2024 Category: Research Source Type: clinical trials
High Intensity Interval Versus Focused Ultrasound on Insulin Resistance in Diabetics With Abdominal Obesity
Conditions: Insulin Resistance; Abdominal Obesity; Diabetes Interventions: Other: High intensity interval exercise; Other: Focused ultrasound Sponsors: Badr University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 22, 2024 Category: Research Source Type: clinical trials
Prevention and Choice for Type 2
Conditions: PreDiabetes Interventions: Behavioral: PACT2 Sponsors: University of Colorado, Denver; American Diabetes Association; High Plains Research Network Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 22, 2024 Category: Research Source Type: clinical trials
Oxidative and Antioxidant Indices to HIIT and Aloe Vera Supplementation in Patients With T2DM
Conditions: Diabetes Type 2 Interventions: Behavioral: Exercise; Dietary Supplement: Aloe vera Sponsors: University of Nis Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 22, 2024 Category: Research Source Type: clinical trials
Photocoagulation or sham laser in addition to conventional anti-VEGF therapy in macular edema associated with TelCaps due to diabetic macular edema or retinal vein occlusion (TalaDME): a study protocol for a multicentric, French, two-group, non-commercial, active-control, observer-masked, non-inferiority, randomized controlled clinical trial
DiscussionThe best management of ME associated with TelCaps is debated, and there have been no randomized study designed to answer this question. Given the fact that TelCaps may affect 30 to 60% of patients with chronic ME due to DR or RVO, a large number of patients could benefit from a specific management of TelCaps. TalaDME aims to establish the clinical and medico-economic benefits of additional targeted laser. The results of TalaDME may raise new recommendations for managing ME and impact healthcare costs.Trial registrationEudraCT: 2018-A00800-55/ NCT03751501. Registration date: Nov. 23, 2018. (Source: Trials)
Source: Trials - April 22, 2024 Category: Research Source Type: clinical trials
EndoBarrier in Obstructive Sleep Apnoea Study
Conditions: Type 2 Diabetes; Obstructive Sleep Apnoea; Obesity Interventions: Device: EndoBarrier Sponsors: Dr Bob Ryder; Association of British Clinical Diabetologists Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 19, 2024 Category: Research Source Type: clinical trials
Real-time Engagement for Learning to Effectively Control Type 2 Diabetes
Conditions: Diabetes Mellitus, Type 2; Lifestyle; Hyperglycemia; Physical Inactivity Interventions: Behavioral: Focused App Prompt; Behavioral: No App Prompt Sponsors: University of Pittsburgh; Dartmouth College; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University of Michigan; San Diego State University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 19, 2024 Category: Research Source Type: clinical trials
The Effect of Pyridoxamine Supplementation on Microvascular Function in Type 2 Diabetes
Conditions: Type 2 Diabetes; Microvascular Function; Retinopathy, Diabetic; Nephropathy, Diabetic; Neuropathy, Diabetic Interventions: Dietary Supplement: Pyridoxamine 300mg per day; Other: Placebo 300mg placebo per day Sponsors: Maastricht University Medical Center; Diabetes Fonds Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 19, 2024 Category: Research Source Type: clinical trials
Comparison of HR011408 and NovoRapid ® in Subjects With Diabetics
Conditions: Diabetes Interventions: Drug: HR011408 injection; HR011408 injection Placebo; Drug: NovoRapid ®; HR011408 injection Placebo; Drug: HR011408 injection Placebo; HR011408 injection Sponsors: Jiangsu HengRui Medicine Co., Ltd. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 19, 2024 Category: Research Source Type: clinical trials
Probiotic Effect on Dietary Nitrate to Plasma Nitrite Production ( OPEDNPN )
Conditions: Hypertension; Cardiovascular Diseases; Diabetes Interventions: Dietary Supplement: Herbiotics Oral + Ent Probiotic Sponsors: Wake Forest University; University of South Florida Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 19, 2024 Category: Research Source Type: clinical trials
Decentralized N=1 Study: A Feasible Approach to Evaluate Individual Therapy Response to Dapagliflozin.
Conditions: Diabetes Mellitus, Type 2; Diabetes Mellitus Type 2 With Proteinuria; Diabetes Mellitus; Diabetes; Diabetes Complications; Albuminuria; Chronic Kidney Diseases; Chronic Kidney Disease Due to Type 2 Diabetes Mellitus; CKD; Proteinuria Interventions: Drug: Dapagliflozin 10mg Tab; Drug: Placebo; Device: Withings BPM Connect; Device: Withings Body+; Diagnostic Test: Hem-Col Capillary Blood Collection Device; Device: MEMS (Medication Electronic Monitoring System) Cap; Behavioral: Questionnaire: participants ' perspectives toward remote data collection Sponsors: University Medical Center Groningen; AstraZeneca Comple...
Source: ClinicalTrials.gov - April 18, 2024 Category: Research Source Type: clinical trials
Placenta Derived Stem Cells for Treating of Chronic Ulcers and Neuropathy
Conditions: Diabetic Foot; Diabetic Neuropathies; Diabetic Foot Ulcer Interventions: Biological: Transplantation of Placenta Derived Stem Cells Sponsors: Michael H Carstens; Ministerio de Salud de Nicaragua; Wake Forest Institute for Regenerative Medicine Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 18, 2024 Category: Research Source Type: clinical trials
Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence
Conditions: Diabetes; Hypertension; High Cholesterol/Hyperlipidemia; Coronary Artery Disease; Congestive Heart Failure; Chronic Lung Disease; Chronic Kidney Diseases; Arrythmia; Stroke; Depression; Anxiety; Pulmonary Embolism; Heart Attack Interventions: Other: Med AAAction intervention Sponsors: University of Tennessee; Sponsor GmbH Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 18, 2024 Category: Research Source Type: clinical trials
Small Bowel Diversion
Conditions: Obesity; Type2 Diabetes Interventions: Procedure: jejuno-ileal bypass; Procedure: jejuno-colic bypass Sponsors: University of Ostrava; Institute for Clinical and Experimental Medicine; Vitkovice Hospital Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 18, 2024 Category: Research Source Type: clinical trials
Continuous Glucose Monitoring, Contingency Management, and Motivational Interviewing for Patients With Type 2 Diabetes in Kansas City
Conditions: Type 2 Diabetes Interventions: Behavioral: Behavioral Intervention with financial rewards and coaching; Behavioral: Control Sponsors: University of Missouri, Kansas City Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 18, 2024 Category: Research Source Type: clinical trials
