A cluster-randomized study to evaluate the effectiveness and cost-effectiveness of the Assessment of Burden of Chronic Conditions (ABCC) tool in South Tyrolean primary care for patients with COPD, asthma, type 2 diabetes, and heart failure: the ABCC South Tyrol study
This study aims to validate the German and Italian versions of the ABCC tool and evaluate its effectiveness and cost-effectiveness in the South Tyrolean Primary Care setting.MethodsThis is a cluster-randomized study involving approximately 400 patients with COPD, asthma, type 2 diabetes, and heart failure who received care from the South Tyrolean General Practices. Initially, the ABCC tool will be translated into German and Italian and validated. Subsequently, half of the participants will use the validated ABCC tool for patient-reported outcome measurement assessments, while the other half will receive usual care. The pri...
Source: Trials - March 20, 2024 Category: Research Source Type: clinical trials

Evaluation of the Chronic Disease Co-Care Pilot Scheme
Conditions: Diabetes Mellitus, Type 2; Hypertension; Chronic Disease; Disease Management; Primary Healthcare Interventions: Combination Product: The Chronic Disease Co-Care (CDCC) Pilot Scheme Sponsors: The University of Hong Kong; Health and Medical Research Fund; Primary Healthcare Office, Hong Kong Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2024 Category: Research Source Type: clinical trials

The Impact of Oral Glutathione on Oxidative Damage and Glycated Hemoglobin (HbA1c) Levels in Type 2 Diabetes Patients
Conditions: Type 2 Diabetes Interventions: Dietary Supplement: enhanced glutathione; Other: placebo comparator Sponsors: S.LAB (SOLOWAYS); Center of New Medical Technologies Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2024 Category: Research Source Type: clinical trials

The Effects of CGM and Connected Pen in T2DM Treated With Multiple Daily Insulin Injections
Conditions: Type 2 Diabetes Treated With Insulin Interventions: Device: Continuous glucose monitoring and use of connected insulinpen for bolus insulin Sponsors: Klavs W ürgler Hansen; Steno Diabetes Center Aarhus, Denmark Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2024 Category: Research Source Type: clinical trials

Remotely Delivered Mindfulness-Based Diabetes Education
Conditions: Type 2 Diabetes Interventions: Behavioral: Remotely delivered Mindfulness-Based Diabetes Education with remote patient monitoring; Behavioral: Standard Diabetes Self Management Education Sponsors: University of Alabama at Birmingham; National Institute on Minority Health and Health Disparities (NIMHD) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2024 Category: Research Source Type: clinical trials

Home-Based Circuit Training in Overweight/Obese Older Adult Patients With Knee Osteoarthritis and Type 2 Diabetes
Conditions: Aerobic Exercise; Strength Training; Glycemic Control; Blood Pressure; Oxidative Stress; Metabolic Syndrome Interventions: Behavioral: 12-week home-based circuit training (HBCT); Behavioral: Standard of care (CONT) Sponsors: Princess Nourah Bint Abdulrahman University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 13, 2024 Category: Research Source Type: clinical trials

A UK Registry for Metabolic and Bariatric Endoscopic Interventions
Conditions: Obesity; Diabetes Mellitus, Type 2 Interventions: Device: Endoscopic gastric suturing; Device: Endoscopic gastric plication; Device: Revisional gastroplasty; Device: Transoral outlet reduction endoscopy (TORe); Device: Duodenal mucosal resurfacing (DMR); Device: Intragastric balloon(s) Sponsors: Cleveland Clinic London Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 11, 2024 Category: Research Source Type: clinical trials

Risk of CKD in Diabetic Patients With MAFLD
Conditions: Type 2 Diabetes Interventions: Diagnostic Test: transient elastography (Fibroscan) Sponsors: Sohag University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 11, 2024 Category: Research Source Type: clinical trials

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of K-757 and K-833 in Overweight/Obese Patients With Type 2 Diabetes
Conditions: Obesity; Type 2 Diabetes Mellitus (T2DM) Interventions: Drug: K-757 and K-833 QD; Drug: K-757 and K-833 BID; Drug: Matching placebo to K-757 and K-833 QD; Drug: Matching placebo to K-757 and K-833 BID Sponsors: Kallyope Inc. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 11, 2024 Category: Research Source Type: clinical trials

The Effect of Semaglutide on Cardiovascular Markers and Liver Function
Conditions: Diabetes Type 2 Interventions: Drug: Semaglutide, 1.0 mg/mL; Drug: Dipeptidyl Peptidase 4 inhibitor Sponsors: Attikon Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 8, 2024 Category: Research Source Type: clinical trials

County Medical Community-based, Cardiovascular Risk Stratified Integrated Care Model: a Pragmatic Cluster Randomised Control Trial
Conditions: Hypertension; Diabetes Mellitus Type 2; Cardiovascular Diseases Interventions: Other: Team-based care; Procedure: Risk-stratified care pathway; Behavioral: Strengthened health education; Other: Financial incentives for integration of care; Other: Supporting health information system Sponsors: Peking University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 8, 2024 Category: Research Source Type: clinical trials

Phenotyping Patients With Type 2 Diabetes Mellitus and Cancer
Conditions: Diabetes Mellitus, Type 2; Cancer Interventions: Other: phenotyping of patients followed at a third-level diabetes centre with cancer Sponsors: Azienda Ospedaliero Universitaria Maggiore della Carita Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 8, 2024 Category: Research Source Type: clinical trials

Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)
Conditions: Type 2 Diabetes Interventions: Drug: Retatrutide; Drug: Placebo Sponsors: Eli Lilly and Company Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2024 Category: Research Source Type: clinical trials

Argentine Registry of Lp(a)
Conditions: Lp(A); Hypercholesterolemia; Cardiovascular Diseases; Diabete Type 2; Hypertension Sponsors: School of Medicine. National University of Cuyo Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2024 Category: Research Source Type: clinical trials

Genetic variability to glp1 treatment
Conditions: Type 2 Diabetes; Obesity Interventions: Genetic: DNA Sequencing and Analysis; Genetic: differential expression analysis with RNA-sequencing (RNA seq) experiments Sponsors: GENGE Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2024 Category: Research Source Type: clinical trials