Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis
Condition: AL Amyloidosis Interventions: Procedure: Autologous Hematopoietic Stem Cell Transplantation; Procedure: Biopsy; Procedure: Biospecimen Collection; Procedure: Bone Marrow Aspiration; Procedure: Bone Marrow Biopsy; Drug: Bortezomib; Procedure: Computed Tomography; Drug: Cyclophosphamide; Dr ug: Daratumumab and Hyaluronidase-fihj; Drug: Dexamethasone; Procedure: Echocardiography; Procedure: Magnetic Resonance Imaging; Drug: Melphalan; Procedure: Positron Emission Tomography; Procedure: Stem Cell Isolation; Other: Survey Administration...
Source: ClinicalTrials.gov - September 5, 2023 Category: Research Source Type: clinical trials
Postoperative Steroid Use in Adolescent Idiopathic Scoliosis and Neuromuscular Scoliosis Patients
Conditions: Neuromuscular Scoliosis; Adolescent Idiopathic Scoliosis Intervention: Drug: Dexamethasone Sponsor: Children's Hospital Los Angeles Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 5, 2023 Category: Research Source Type: clinical trials
Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis
Condition: AL Amyloidosis Interventions: Procedure: Autologous Hematopoietic Stem Cell Transplantation; Procedure: Biopsy; Procedure: Biospecimen Collection; Procedure: Bone Marrow Aspiration; Procedure: Bone Marrow Biopsy; Drug: Bortezomib; Procedure: Computed Tomography; Drug: Cyclophosphamide; Dr ug: Daratumumab and Hyaluronidase-fihj; Drug: Dexamethasone; Procedure: Echocardiography; Procedure: Magnetic Resonance Imaging; Drug: Melphalan; Procedure: Positron Emission Tomography; Procedure: Stem Cell Isolation; Other: Survey Administration...
Source: ClinicalTrials.gov - September 5, 2023 Category: Research Source Type: clinical trials
Postoperative Steroid Use in Adolescent Idiopathic Scoliosis and Neuromuscular Scoliosis Patients
Conditions: Neuromuscular Scoliosis; Adolescent Idiopathic Scoliosis Intervention: Drug: Dexamethasone Sponsor: Children's Hospital Los Angeles Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 5, 2023 Category: Research Source Type: clinical trials
Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis
Condition: AL Amyloidosis Interventions: Procedure: Autologous Hematopoietic Stem Cell Transplantation; Procedure: Biopsy; Procedure: Biospecimen Collection; Procedure: Bone Marrow Aspiration; Procedure: Bone Marrow Biopsy; Drug: Bortezomib; Procedure: Computed Tomography; Drug: Cyclophosphamide; Dr ug: Daratumumab and Hyaluronidase-fihj; Drug: Dexamethasone; Procedure: Echocardiography; Procedure: Magnetic Resonance Imaging; Drug: Melphalan; Procedure: Positron Emission Tomography; Procedure: Stem Cell Isolation; Other: Survey Administration...
Source: ClinicalTrials.gov - September 5, 2023 Category: Research Source Type: clinical trials
Postoperative Steroid Use in Adolescent Idiopathic Scoliosis and Neuromuscular Scoliosis Patients
Conditions: Neuromuscular Scoliosis; Adolescent Idiopathic Scoliosis Intervention: Drug: Dexamethasone Sponsor: Children's Hospital Los Angeles Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 5, 2023 Category: Research Source Type: clinical trials
Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis
Condition: AL Amyloidosis Interventions: Procedure: Autologous Hematopoietic Stem Cell Transplantation; Procedure: Biopsy; Procedure: Biospecimen Collection; Procedure: Bone Marrow Aspiration; Procedure: Bone Marrow Biopsy; Drug: Bortezomib; Procedure: Computed Tomography; Drug: Cyclophosphamide; Dr ug: Daratumumab and Hyaluronidase-fihj; Drug: Dexamethasone; Procedure: Echocardiography; Procedure: Magnetic Resonance Imaging; Drug: Melphalan; Procedure: Positron Emission Tomography; Procedure: Stem Cell Isolation; Other: Survey Administration...
Source: ClinicalTrials.gov - September 5, 2023 Category: Research Source Type: clinical trials
Postoperative Steroid Use in Adolescent Idiopathic Scoliosis and Neuromuscular Scoliosis Patients
Conditions: Neuromuscular Scoliosis; Adolescent Idiopathic Scoliosis Intervention: Drug: Dexamethasone Sponsor: Children's Hospital Los Angeles Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 4, 2023 Category: Research Source Type: clinical trials
Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis
Condition: AL Amyloidosis Interventions: Procedure: Autologous Hematopoietic Stem Cell Transplantation; Procedure: Biopsy; Procedure: Biospecimen Collection; Procedure: Bone Marrow Aspiration; Procedure: Bone Marrow Biopsy; Drug: Bortezomib; Procedure: Computed Tomography; Drug: Cyclophosphamide; Dr ug: Daratumumab and Hyaluronidase-fihj; Drug: Dexamethasone; Procedure: Echocardiography; Procedure: Magnetic Resonance Imaging; Drug: Melphalan; Procedure: Positron Emission Tomography; Procedure: Stem Cell Isolation; Other: Survey Administration...
Source: ClinicalTrials.gov - September 4, 2023 Category: Research Source Type: clinical trials
The effect of perioperative of dexamethasone on postoperative complications after pancreaticoduodenectomy (PANDEX): a study protocol for a pragmatic multicenter randomized controlled trial
DiscussionThe PANDEX trial is the first randomized controlled trial concerning the effect of dexamethasone on postoperative complications of patients undergoing PD, with the hypothesis that the intraoperative use of dexamethasone can reduce the incidence of postoperative complications and improve short-term outcomes after PD. The results of the present study will guide the perioperative use of dexamethasone and help improve the clinical management of post-pancreatectomy patients.Trial registrationClinicalTrials.gov NCT05567094. Registered on 30 September 30 2022 (Source: Trials)
Source: Trials - September 2, 2023 Category: Research Source Type: clinical trials
