What would you like to ask the BMJ Cardiovascular Team of the Year?
For the new doc2doc BMJ Guide to Cardiology, we are interviewing the BMJ Cardiovascular Team of The Year. What questions would you like me to ask them? Please submit your questions below...    Cardiovascular Team of the Year  The Birmingham Atrial Fibrillation Team University of Birmingham Centre for Cardiovascular Sciences and Sandwell and West Birmingham Hospitals NHS Trust, West Midlands The team developed a new bleeding risk score specifically for use in Atrial Fibrillation.  HAS-BLED provides clinicians with a validated tool to assess bleeding risk, allowing them to identify modifiable ble...
Source: Doc2Doc BMJ Cardiology - October 18, 2013 Category: Cardiology Authors: Matthew Billingsley Source Type: forums

Recurrence of DVT while on newer anticoagulant therapy ( Rivoroxaban 20mg once daily).
Pt did not tolerate warfarin due to very Labile INR with smallest changes in the dose.  Indication :Right MCA infarct with AF with Recurrent DVT's and PE. Pt has recurrence of DVT while being on Rivoroxaban for 6 wks. Any comments regarding change in management? (Source: Doc2Doc BMJ Cardiology)
Source: Doc2Doc BMJ Cardiology - October 15, 2013 Category: Cardiology Authors: ajaygupta480 Source Type: forums

FDA Investigation Finds No Excess Bleeding Risk for Dabigatran
In its latest assessment of a highly controversial issue, the FDA has found no indication that bleeding rates for dabigatran (Pradaxa, Boehringer-Ingelheim) are any higher than the bleeding rates for warfarin. The FDA investigation was in response to the large number of post-marketing reports of bleeding in people taking dabigatran. Click here to for the full FDA statement. Here is the first paragraph of the statement: The U.S. Food and Drug Administration (FDA) has evaluated new information about the risk of serious bleeding associated with use of the anticoagulants (blood thinners) dabigatran (Pradaxa) and warfarin (Co...
Source: CardiologyNetwork.com - October 13, 2013 Category: Cardiology Authors: Indian Diabetics Foundation Team Source Type: forums

Rivaroxaban Gains FDA Indications for Treating and Preventing DVT and PE
The FDA has expanded the indication for rivaroxaban (Xarelto, Johnson & Johnson) to include the treatment of deep-vein thrombosis (DVT) and pulmonary embolism (PE) and to reduce the risk for recurrent DVT and PE. The oral anticoagulant is already approved to reduce postsurgical risk for DVT and PE  after hip- and knee-replacement surgery and to reduce the risk for stroke in people with atrial fibrillation. The new indication was granted under the FDA’s priority review program. “Xarelto is the first oral anti-clotting drug approved to treat and reduce the recurrence of blood clots since the approval of warfarin nea...
Source: CardiologyNetwork.com - October 13, 2013 Category: Cardiology Authors: Indian Diabetics Foundation Team Source Type: forums

What's the best antiplatelet regime for patients on wafarin?
I often struggle with this for patients in AF who end up having a stent and often find that aspirin plus clopdiogrel plus warfarin can be a very difficult combination particularly when a drug eluting stent has been implanted! I'm pleased to see a trial that supports what I think many cardiologists do in practice which is warfarin and clopidogrel only (plus a PPI!)http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)62177-1/abstractWhat's your antiplatelet regime of choice in this situation?sadian (Source: Doc2Doc BMJ Cardiology)
Source: Doc2Doc BMJ Cardiology - February 23, 2013 Category: Cardiology Authors: sadian Source Type: forums

Upper Extremity DVT with subclavians/piccs
I placed a subclavian in a patient with pylephlebitis, put the dude on hepatin and coumadin. All is well. A week later he complains of UE pain and swelling in ipsilateral arm (pt refused IJ). Got U/S and kablamo: clot running from basilic through subclavian. We pulled the line slllooowwwwllllyyyy (he needed placement with long term iv abx so he eventually got an IJ tunnelled picc). we had to heparinize the guy for his portal/superior mesenteric vein clot. How often do you guys see them? How often do you you sweat pulling the line? should you pull the line if its around a picc in a pt who needs long term IV access?...
Source: Student Doctor Network Forums - January 30, 2013 Category: Universities & Medical Training Authors: VentdependenT Tags: Critical Care Source Type: forums

ivc filters for thromboembolic disease
my colleague and i spent about 30mins debating this case yesterday70 year old manpreviously fit and healthydvt and pe post flight to us last may6 months warfarin very breathless - echo mild rv dilatation, right heart cath 3 months in normal pa pressureswarfarin stopped at 6 months and then further dvt and pe 8 days later - now on lifelong warfarinhad episode about 6 weeks ago with further leg swelling and chest pain for 1 day, didn't seek medical advice and no inr recordedwould you recommend an ivc filter in his case? We both had different ideas so I'm keen to hear what others think?sadian (Source: Doc2Doc BMJ Cardiology)
Source: Doc2Doc BMJ Cardiology - January 25, 2013 Category: Cardiology Authors: sadian Source Type: forums