Recurrence of DVT while on newer anticoagulant therapy ( Rivoroxaban 20mg once daily).

Pt did not tolerate warfarin due to very Labile INR with smallest changes in the dose.  Indication :Right MCA infarct with AF with Recurrent DVT's and PE. Pt has recurrence of DVT while being on Rivoroxaban for 6 wks. Any comments regarding change in management?
Source: Doc2Doc BMJ Cardiology - Category: Cardiology Authors: Source Type: forums