Immunoadsorption Versus Immunoglobulins for Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Condition:   CIDP Interventions:   Device: Immunoadsorption;   Biological: Immunoglobulins Sponsors:   University of Ulm;   Miltenyi Biomedicine GmbH Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 11, 2021 Category: Research Source Type: clinical trials

Intravenous immunoglobulin and intravenous methylprednisolone as optimal induction treatment in chronic inflammatory demyelinating polyradiculoneuropathy: protocol of an international, randomised, double-blind, placebo-controlled trial (OPTIC)
DiscussionIn case of superiority of the combined treatment, patients will experience the advantages of two proven efficacious treatments, namely rapid improvement due to IVIg and long-term remission due to corticosteroids. Long-term remission would reduce the need for maintenance IVIg treatment and may decrease health care costs. Additionally, we expect that the combined treatment leads to a higher proportion of patients with improvement as some patients who do not respond to IVIg will respond to corticosteroids. Risks of short and long-term additional adverse events of the combined treatment need to be assessed.Trial regi...
Source: Trials - February 19, 2021 Category: Research Source Type: clinical trials

Effects of Single Plasma Exchange and Double Filtration Plasmapheresis (DFPP) on Peripheral Lymphocyte Phenotypes in Patients With Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Condition:   Polyradiculoneuropathy, Chronic Inflammatory Demyelinating Intervention:   Biological: Blood sampling Sponsor:   Centre Hospitalier Universitaire de Nīmes Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 8, 2021 Category: Research Source Type: clinical trials