An end to the routine use of manual thrombectomy in STEMI?
Earlier this month the results of long awaited TOTAL trial were presented at the ACC meeting and simultaneously published in NEJM. TOTAL is the largest randomised trial to date which investigated the routine upfront manual thrombectomy with PCI alone in STEMI. 10,732 patients with STEMI undergoing primary PCI were randomised. The primary outcome was a composite of death from cardiovascular causes, recurrent myocardial infarction, cardiogenic shock, or NYHA class IV heart failure within 180 days. The key safety outcome was stroke within 30 days. Manual aspiration thrombectomy was associated with lower rates of incomple...
Source: Doc2Doc BMJ Cardiology - March 26, 2015 Category: Cardiology Authors: Heart Matters Source Type: forums
Re: PCSK9 inhibitors reduce cardiovascular events, preliminary data show
(Source: BMJ Comments)
Source: BMJ Comments - March 25, 2015 Category: Journals (General) Source Type: forums
A large cohort study suggests that aspirin prophylaxis only benefits people with a prior cardiovascular event
Conclusions
In patients with stable coronary artery disease and hypertension, aspirin use was associated with reduced risk for adverse cardiovascular outcomes among those with prior ischemic events. Among patients with no prior ischemic events, aspirin use was not associated with a reduction in risk.
COMMENT: The determining the risk/benefit ratio of prophylactic aspirin use for the prevention of cardiovascular events has become a complicated issue. The current recommendations from the CDC http://www.cdc.gov/heartdisease/aspirin.htm recommend aspirin prophylaxis in those with prior cardiovascular events. Th...
Source: Doc2Doc BMJ Cardiology - March 2, 2015 Category: Cardiology Authors: diabetesMD Source Type: forums
Higher Whole Grain Intake Linked to Lower Mortality
In preparation for my case ofthe week i ran accoss severay articles on diet that I felt would be of interest to the readers of the Cardiology forum. i am posting them today.
Higher Whole Grain Intake Linked to Lower Mortality
By Jenni Whalen from 6 January 2015 NEJM Journal Watch
Edited by David G. Fairchild, MD, MPH
Higher intake of whole grains is associated with reduced overall mortality and especially cardiovascular mortality, according to a JAMA Internal Medicine study.
Researchers followed approximately 74,000 women from the Nurses' Health Study from 1984 to 2010, and nearly 44,000 men from the Health...
Source: Doc2Doc BMJ Cardiology - March 2, 2015 Category: Cardiology Authors: diabetesMD Source Type: forums
