Shedding light on the dark genome: Long Non-coding RNA in Cardiovascular, Lung, Blood, and Sleep Research (R01 - Clinical Trial Not Allowed)
Funding Opportunity RFA-HL-19-011 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to foster research on human long non-coding RNAs (lncRNAs) to understand their roles in controlling the gene regulatory networks underpinning normal Heart, Lung, Blood and Sleep (HLBS) homeostatic and disease processes. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 17, 2017 Category: Research Source Type: funding

Why Project Outcomes Matter in your Interim and Final RPPR
The next time you are filling out your interim or final Research Performance Progress Report (RPPR) for your NIH grant, pay special attention to writing the project Outcomes section (Section I). That’s because any project outcomes submitted on or after Oct. 1, 2017 will be made available to the general public via NIH’s Research Portfolio Online Reporting Tool (RePORTER). You may wonder why the scientific community needs to report on outcomes and why we are making the outcomes available to the public. Reviewing reported outcomes is part of our stewardship of the public’s investment in research. Publicly posting grant ...
Source: NIH Extramural Nexus - November 16, 2017 Category: Research Authors: Mike Lauer Tags: blog Open Mike General RePORT Source Type: funding

Notice of Upcoming Webinar for the Strong Heart Study (SHS) - Coordinating Center (CC) Solicitation
Notice NOT-HL-17-562 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 16, 2017 Category: Research Source Type: funding

Mentored Career Development Award to Promote Faculty Diversity in Biomedical Research (K01) (Clinical Trial Required)
Funding Opportunity RFA-HL-18-027 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications to enhance the pool of of highly trained investigators from diverse backgrounds underrepresented in research. It is targeted toward individuals whose basic, clinical, and translational research interests are grounded in the advanced methods and experimental approaches needed to solve problems related to cardiovascular, pulmonary, and hematologic diseases and sleep disorders in the general and health disparities populations. This FOA invites applications from Institutions with el...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 9, 2017 Category: Research Source Type: funding

Environmental Exposures and Health: Exploration of Non-Traditional Settings (R21 Clinical Trial Optional)
Funding Opportunity PA-18-160 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to encourage interdisciplinary research aimed at promoting health, preventing and limiting symptoms and disease, and reducing health disparities across the lifespan for those living or spending time in non-traditional settings (i.e. playgrounds and nursing homes). These settings result in exposure to environmental pollutants and toxins that result in health risks, symptoms, and other health conditions/diseases; including lower respiratory disease, chronic obstructive pulmonary disease,...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 7, 2017 Category: Research Source Type: funding

Environmental Exposures and Health: Exploration of Non-Traditional Settings (R01 Clinical Trial Optional)
Funding Opportunity PA-18-142 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to encourage interdisciplinary research aimed at promoting health, preventing and limiting symptoms and disease, and reducing health disparities across the lifespan for those living or spending time in non-traditional settings (i.e. playgrounds and nursing homes). These settings result in exposure to environmental pollutants and toxins that result in health risks, symptoms, and other health conditions/diseases; including lower respiratory disease, chronic obstructive pulmonary disease,...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 7, 2017 Category: Research Source Type: funding

Research to Advance the Understanding and Management of the Multiple Organ Dysfunction Syndrome in Children (R01 Clinical Trial Optional)
Funding Opportunity PAR-18-091 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to establish a program of research to advance the understanding, prevention and treatment of pediatric multiple organ dysfunction syndrome (MODS). Given the prevalence and associated morbidity and mortality of MODS in children, the current lack of understanding underscores the need for more basic, exploratory and longitudinal research. Possible topics of study include, but are not limited, to the epidemiology, pathophysiology, monitoring, and treatment of MODS. Studies that assess spe...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 6, 2017 Category: Research Source Type: funding

Physical Activity and Weight Control Interventions Among Cancer Survivors: Effects on Biomarkers of Prognosis and Survival (R21 Clinical Trial Optional)
Funding Opportunity PAR-18-016 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages transdisciplinary and translational research that will identify the specific biological or biobehavioral pathways through which physical activity and/or weight control (either weight loss or avoidance of weight gain) may affect cancer prognosis and survival. Research applications should test the effects of physical activity, alone or in combination with weight control (either weight loss or avoidance of weight gain), on biomarkers of cancer prognosis among cancer survivors identified by prev...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 3, 2017 Category: Research Source Type: funding

Physical Activity and Weight Control Interventions Among Cancer Survivors: Effects on Biomarkers of Prognosis and Survival (R01 Clinical Trial Optional)
Funding Opportunity PAR-18-006 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages transdisciplinary and translational research that will identify the specific biological or biobehavioral pathways through which physical activity and/or weight control (either weight loss or avoidance of weight gain) may affect cancer prognosis and survival. Research applications should test the effects of physical activity, alone or in combination with weight control (either weight loss or avoidance of weight gain), on biomarkers of cancer prognosis among cancer survivors identified by prev...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 3, 2017 Category: Research Source Type: funding

Improving Outcomes in Cancer Treatment-Related Cardiotoxicity (R21 Clinical Trial Optional)
Funding Opportunity PA-18-013 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages collaborative applications that will contribute to the identification and characterization of patients at risk of developing cancer treatment-related cardiotoxicity. The primary intent is to mitigate cardiovascular dysfunction while optimizing cancer outcomes. To accomplish this, methods that evaluate cardiac risk prior to treatment and integrate evidence-based cancer treatment regimens with screening, diagnostic, and/or management strategies are sought. Research applications should focus on ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 2, 2017 Category: Research Source Type: funding

Improving Outcomes in Cancer Treatment-Related Cardiotoxicity (R01 Clinical Trial Optional)
Funding Opportunity PA-18-003 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages collaborative applications that will contribute to the identification and characterization of patients at risk of developing cancer treatment-related cardiotoxicity. The primary intent is to mitigate cardiovascular dysfunction while optimizing cancer outcomes. To accomplish this, methods that evaluate cardiac risk prior to treatment and integrate evidence-based cancer treatment regimens with screening, diagnostic, and/or management strategies are sought. Research applications should focus on ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 2, 2017 Category: Research Source Type: funding

Mentored Career Development Award to Promote Faculty Diversity in Biomedical Research (K01) - (Clinical Trials Not Allowed)
Funding Opportunity RFA-HL-18-026 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications to enhance the pool of of highly trained investigators from diverse backgrounds underrepresented in research. It is targeted toward individuals whose basic, clinical, and translational research interests are grounded in the advanced methods and experimental approaches needed to solve problems related to cardiovascular, pulmonary, and hematologic diseases and sleep disorders in the general and health disparities populations. This FOA invites applications from Institutions with el...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 26, 2017 Category: Research Source Type: funding

NHLBI Program Project Applications (P01 - Clinical Trials Optional)
Funding Opportunity PAR-18-405 from the NIH Guide for Grants and Contracts. The National Heart, Lung, and Blood Institute (NHLBI) Program Project Grant (P01) supports research related to fundamental processes and diseases of the heart, blood and lymphatic vessels, lungs, and blood, including transfusion medicine, blood resources, and sleep disorders other programs including implementation science, health disparities, and translation research that address the mission of the Institute. This FOA requires a minimum of three interrelated research projects that investigate a complex biomedical theme or research question. The ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 20, 2017 Category: Research Source Type: funding

A Sampling of Recent Literature on the Scientific Workforce
As NIH continues its work to better understand the many factors that influence the stability of the biomedical workforce, we wanted to take a moment to discuss some recent papers that highlight the need to take new measures to support early and mid-career researchers. Earlier this year, we discussed a paper by our NIH colleagues who looked at data on the shifting demographics of lead principal investigators (PIs) on NIH and National Heart Lung and Blood Institute (NHLBI) research project grants. One of their findings is a decline in the representation of PIs aged 41-55. A recent paper by Michael Levitt (Stanford University...
Source: NIH Extramural Nexus - October 18, 2017 Category: Research Authors: Mike Lauer Tags: Open Mike Biomedical Workforce Early Stage Investigators Source Type: funding

NHLBI Announces Plans to Fund a Jackson Heart Study Exam 4
Notice NOT-HL-17-542 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 18, 2017 Category: Research Source Type: funding