Longitudinal Early Advance Care Planning Discussions and Documentation (LEADD) Program: An Exploratory Study in Adolescents and Young Adults (AYAs) Receiving Hematopoietic Stem Cell Transplant
Condition:   Hematopoietic Stem Cell Transplantation Intervention:   Behavioral: Advance Care Planning conversations Sponsor:   National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 4, 2022 Category: Research Source Type: clinical trials

Adolescents and Young Adults (AYAs) With Advanced Cancer
Condition:   Adolescent and Young Adult Cancer Patient Interventions:   Behavioral: Symptom Management for Improved Physical and Emotional Wellbeing (SMILE);   Behavioral: Education Control Arm Sponsors:   Duke University;   National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 25, 2022 Category: Research Source Type: clinical trials

Opening the Conversation: study protocol for a Phase III trial to evaluate a couple-based intervention to reduce reproductive and sexual distress among young adult breast and gynecologic cancer survivor couples
This study evaluates the efficacy of a virtual couple-based intervention called Opening the Conversation (OC). The OC intervention is grounded in theory and evidence-based practice and was adapted to improve coping and communication specifically in relation to RSH concerns after cancer.MethodsThis Phase III trial is conducted in a fully remote setting and enrolls young adult couples (current age 18 –44 years) with a history of breast or gynecologic cancer (stage 1–4, diagnosed under age 40) within the past 6 months to 5 years. Eligible dyads are recruited from across the USA. The target sample size is 100 couples. Dyad...
Source: Trials - September 2, 2022 Category: Research Source Type: clinical trials

A Second Infusion (Early Reinfusion) of Tisagenlecleucel in Children and Young Adults With B-Cell Acute Lymphoblastic Lymphoma (B-ALL)
Condition:   B-cell Acute Lymphoblastic Leukemia Intervention:   Biological: Tisagenlecleucel Sponsors:   Memorial Sloan Kettering Cancer Center;   Novartis Pharmaceuticals Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 15, 2022 Category: Research Source Type: clinical trials