Intrathecal bumetanide has analgesic effects through inhibition of NKCC1
(Neural Regeneration Research) Accumulating evidence has demonstrated that the sodium-potassium-chloride co-transporter 1 and potassium-chloride co-transporter 2 have a role in the modulation of pain transmission at the spinal level through chloride regulation in the pain pathway and by effecting neuronal excitability and pain sensitization. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 16, 2014 Category: Global & Universal Source Type: news

Comparison Of 3 Water Pills For Heart Failure Finds The Most Effective May Be The Least Prescribed
Loop diuretics, more commonly known as water pills, are the most widely prescribed heart failure medications, but few studies had extensively compared their effectiveness until Yale School of Medicine researchers examined three approved loop diuretics and found that even though one of them might offer more benefit, it is rarely prescribed. Published in the early edition of the Journal of the American College of Cardiology, the research compared the potential benefits of using one of three loop diuretics: toresemide, furosemide, and bumetanide... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 3, 2013 Category: Consumer Health News Tags: Heart Disease Source Type: news

Updated national IV monograph on Bumetanide
Source: Medusa Area: News An updated IV monograph on Bumetanide is now available from the NHS injectable medicines guide website (Medusa). Please see the link below for access (registration required). (Source: NeLM - News)
Source: NeLM - News - February 21, 2013 Category: Drugs & Pharmacology Source Type: news