Clinical Study of Breast Conserving Surgery Combined With Intraoperative Radiotherapy for Early Breast Cancer
Conditions: Breast Cancer; HER2-negative Breast Cancer Interventions: Procedure: radiotherapy Sponsors: Hebei Medical University Fourth Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 19, 2024 Category: Research Source Type: clinical trials

Preoperative Accelerated Partial Breast Irradiation in Patients With Locally Recurrent or Second Primary Breast Cancer
Conditions: Breast Cancer Interventions: Radiation: Preoperative accelerated partial breast irradiation; Procedure: Breast conserving surgery; Procedure: Sentinel node procedure; Procedure: Biopsy track removal Sponsors: The Netherlands Cancer Institute Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials

SRG-514 Administered Intraoperatively to Patients Undergoing Breast-conserving Cancer Surgery
Conditions: Breast Cancer Interventions: Drug: SRG-514 Sponsors: SURGE Therapeutics Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 8, 2024 Category: Research Source Type: clinical trials

Manual Lymphatic Drainage Breast Massage in Breast Cancer Patients After Breast Conserving Surgery
Conditions: Anatomic Stage 0 Breast Cancer AJCC v8; Anatomic Stage IA Breast Cancer AJCC v8; Localized Breast Carcinoma Interventions: Other: Lymphedema Management; Other: Questionnaire Administration; Radiation: Adjuvant breast radiation therapy Sponsors: University of Southern California; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2024 Category: Research Source Type: clinical trials

HYPofractionated Adjuvant RadioTherapy in 1 versus 2 weeks in high-risk patients with breast cancer (HYPART): a non-inferiority, open-label, phase III randomised trial
In this study, we will compare a 1-week schedule of hypofractionated adjuvant whole breast/chest wall and/or regional nodal radiotherapy against 2 weeks for locoregional disease control, toxicities, quality of life (QoL), survival and second cancers after primary surgery in patients with breas t cancer.MethodsEligible patients with breast cancer after mastectomy or breast conserving surgery (BCS) will be treated with a radiotherapy dose of 26 Gy in 5 fractions over 1 week in the study arm and 34 Gy in 10 fractions over 2 weeks in the control arm. The primary endpoint of this noninferiority study will be locoregional tumour...
Source: Trials - January 2, 2024 Category: Research Source Type: clinical trials

Quality of Life and Cosmetic Outcomes of Breast-Conserving Surgery According to Localization Method
Conditions: Breast Cancer Interventions: Procedure: Wire-guided surgery; Procedure: Radioactive seed localization; Procedure: Intraoperative ultrasound localization Sponsors: Hospital Clinic of Barcelona Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 29, 2023 Category: Research Source Type: clinical trials

Conserving Surgery in Inflammatory Breast Cancer After Neoadjuvant Chemotherapy
Conditions: Inflammatory Breast Cancer Interventions: Procedure: Breast conserving surgery; Procedure: Radical modified mastectomy Sponsors: Fondazione Policlinico Universitario Agostino Gemelli IRCCS Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 14, 2023 Category: Research Source Type: clinical trials

Repeat Breast Conserving Surgery Followed by Daily Partial Breast Irradiation in Ipsilateral Breast
Conditions: Breast Cancer; Tumor, Breast Interventions: Radiation: Radiation Therapy Sponsors: Case Comprehensive Cancer Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 13, 2023 Category: Research Source Type: clinical trials

Comparing the QoR of PECS Block and GA in Breast-conserving Surgery With Sentinel Lymph Node Biopsy
Conditions: Breast Cancer; Pectoral Nerves Block; Breast-Conserving Surgery; Sentinel Lymph Node Biopsy Interventions: Combination Product: PECS II combined with intercostal nerve blockade;; Combination Product: General anesthesia with laryngeal mask Sponsors: Jun Zhang Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 7, 2023 Category: Research Source Type: clinical trials

Implant-based Breast Reconstruction and Mastectomy With Fat Grafting After Breast Conserving Surgery and Radiotherapy
Conditions: Breast Cancer Interventions: Procedure: Immediate tissue expander and lipofilling after mastectomy Sponsors: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano; Morgagni Pierantoni Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 7, 2023 Category: Research Source Type: clinical trials

Survival of BCS vs Mx in Asymptomatic Screen-detected NPBC
Conditions: Breast Cancer Interventions: Procedure: Breast Conserving Surgery; Procedure: Mastectomy Sponsors: Peking Union Medical College Hospital Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 26, 2023 Category: Research Source Type: clinical trials

Reoperation Rate in Breast-Conserving Surgery Using Confocal Histolog ® Scanner for Intraoperative Margin Assessment
Conditions:   Breast Cancer - Ductal Carcinoma in Situ (DCIS);   Breast-Conserving Surgery Intervention:   Device: Histolog Scanner Sponsors:   SamanTree Medical SA;   St. Vincenz Krankenhaus GmbH, Paderborn Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 14, 2023 Category: Research Source Type: clinical trials