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Protocol for Synpotic reporting of Breast excision specimen with diagnosis of Ductal Carcinoma In Situ (DCIS) of the BreastProtocol applies to DCIS without invasive carcinoma or microinvasion.The complete pathology report should include following parameters.Specimen type.___ Partial breast___ Total breast (including nipple and skin)___ Other (specify): ___ Not specified Procedure ___ Excision without wire-guided localization___ Excision with wire-guided localization___ Total mastectomy (including nipple and skin)___ Other (specify): _______________________________ Not specified Lymph Nod...
Source: Oncopathology - August 25, 2011 Category: Cancer & Oncology Tags: Protocol for Synpotic reporting of Breast excision specimen with diagnosis of Ductal Carcinoma In Situ (DCIS) of the Breast Source Type: blogs
Breast Carcinoma vs. Pulmonary Adenocarcinoma
Some authors have estimated that 4-9% of patients with breast carcinoma will eventually develop second pulmonary carcinomas. As a result, many pathologists have been faced with the problem of trying to determine whether a particular lung carcinoma represents metastatic breast carcinoma or a new primary pulmonary adenocarcinoma. This month, we will briefly review antibodies that may be useful in addressing this differential diagnostic problem.GCDFP-15(gross cystic disease fluid protein-15): This marker has good specificity for breast carcinoma, although its sensitivity is not high, as only about 50% of breast carcinomas exp...
Source: Oncopathology - December 30, 2010 Category: Cancer & Oncology Tags: Breast Carcinoma vs. Pulmonary Adenocarcinoma Source Type: blogs
Work up of Carcinoma of Unknown Primary (CUP)
It is often important to determine the site of origin of a metastatic carcinoma of unknown primary site, particularly because this may affect the choice of the treatment. Determination of the primary site may take several steps.Clinical features, such as age, sex, and site of metastases may give a first indication.A detailed pathologic examination of the most accessible biopsied tissue specimen is mandatory in CUP cases. Pathologic evaluation typically consists of hematoxylin-and-eosin stains and immunohistochemical tests.Electron microscopy is rarely used currently, although it may beselectively useful when making treatme...
Source: Oncopathology - May 4, 2009 Category: Cancer & Oncology Tags: Work up of Carcinoma of Unknown Primary (CUP) Source Type: blogs
