Further Demographic Analyses of NIH R01 Grant Outcomes of T32 Postdoctoral Participants
Introduction Postdoctoral NIH T32 programs aim to provide select trainees with experience to enable successful career and research development. In a previous posting, we presented NIH career development, or K award, and R01 equivalent research grant outcomes of participants in post-doctoral T32 programs. We showed that that men with MD-PhD degrees had the highest rates for R01 application submission and award receipt (as PI). Women comprised a greater proportion of trainees over time. Serving as PI on a K-awards predicted a substantially higher rate of later support as PI on R01 awards. Here we present further analyses foc...
Source: NIH Extramural Nexus - July 27, 2021 Category: Research Authors: Mike Lauer Tags: blog Open Mike Source Type: funding

Data on Implementing NIH ’s Next Generation Researchers Initiative
Discussion Rate” is, like the Funding Rate a person-based metric, and is calculated as the percent of applicants (actually people designated as PI’s on an application) who had at least one application make it to the discussion stage of peer review. As Table 2 indicates, discussion and funding rates in FY 2020 are higher for women in the At Risk and New Not Early groups, but not for the Early Stage and Established groups. Women comprise a greater proportion of Early-Stage Investigator applicants (46%) than any of the other groups including New Investigators, At Risk Investigators and Established Investigators (e.g., wom...
Source: NIH Extramural Nexus - July 12, 2021 Category: Research Authors: Mike Lauer Tags: blog Open Mike at risk investigators Early Stage Investigators ESI funding Funding data NGRI scientific workforce diversity Source Type: funding

NIH Seeking Feedback on Consent Language Resource to Foster Participant Specimen and Data Sharing
  Lyric Jorgenson, NIH Acting Associate Director for Science Policy and Acting Director of the Office of Science Policy NIH is committed to ensuring that study participants are equal partners in research and have input into how their data and biospecimens are collected and used in the future.  At the heart of any research effort lies the need for transparent and clear conversations between researchers and prospective participants about mutual goals and expectations regarding sharing practices. To assist in facilitating this dialogue, NIH has been working with stakeholders to identify informed consent language “best...
Source: NIH Extramural Nexus - July 2, 2021 Category: Research Authors: Mike Lauer and Lyric Jorgenson Tags: blog Open Mike Data sharing Request For Information (RFI) Source Type: funding

New FY 2020 RCDC Categories and Funding Data are Available (Including for Coronaviruses)
NIH recently updated its Research, Condition, and Disease Classification (RCDC) system with FY 2020 actual spending data and estimates for FY 2021 and 2022. “Coronaviruses” is a new category as part of this update. This category covers Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS), and all types of other coronaviruses. Footnote #28 on the RCDC Categorical Spending page indicates that the FY 2020 actuals include obligations from resources specified for NIH in FY 2020 COVID-19 related emergency supplemental appropriations and funding from FY 2020 annual appropriations. FY 2021 and FY 2...
Source: NIH Extramural Nexus - June 30, 2021 Category: Research Authors: NIH Staff Tags: New Resources coronavirus NIH budget RCDC Source Type: funding

An Update on Implementing ACD Recommendations on Changing the Culture to End Sexual Harassment
We presented real-life scenarios presented during the ACD meeting to help put the data into perspective. Have a look at the cases. Table 2 Finding / Outcome Sexual Harassment Only Other Total N (%) 192 (61.1) 122 (38.9) Letter to Institution 131 (68.2) 95 (77.9) Formal Investigation 111 (57.8) 50 (41.0) Title IX Referral 46 (24.0) 20 (16.4) Allegation Substantiated 48 (25.0) 23 (18.9) PI Removed 54 (28.1) 21 (17.2) Other Grant Actions 22 (11.5) 5 (4.1) Safety Actions 32 (16.7) 26 (21.3) Left Institution 50 (26.0) 11 (9.0) Removed from Peer Review 87 (45.3) 38 (31.1) Closed or Resolved 163 (84.9) 10...
Source: NIH Extramural Nexus - June 29, 2021 Category: Research Authors: Mike Lauer Tags: blog Open Mike anti-sexual harassment Source Type: funding

Common Data Elements: Increasing FAIR Data Sharing
This article was originally published in the National Library of Medicine’s blog, Musings from the Mezzanine. Carolina Mendoza-Puccini, MD, CDE Program Officer, Division of Clinical Research, National Institute of Neurological Disorders and Stroke (NINDS) Kenneth J. Wilkins, PhD, Mathematical Statistician, Biostatistics Program and Office of Clinical Research Support, Office of the Director, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Previous posts published in Musings from the Mezzanine have explained the importance of health data standards and their role as the backbone of interop...
Source: NIH Extramural Nexus - June 24, 2021 Category: Research Authors: Carolina Mendoza-Puccini and Kenneth J. Wilkins Tags: blog Open Mike common data elements Data sharing FAIR Source Type: funding

New and Updated Resources Available to Help Design Rigorous Clinical Trials
David M. Murray, Ph.D., NIH Associate Director for PreventionDirector, Office of Disease Prevention We have embarked on a series of initiatives at NIH in recent years to enhance the quality, efficiency, accountability, and transparency of our supported clinical research. While we are all making great progress, our concerns about clinical trials that are overly complex, have small sample sizes, or rely on surrogate end points that lack clinical relevance remain. One resource to help address these concerns is the NIH Research Methods Resources website that NIH’s Office of Disease Prevention (ODP) launched in 2017. Since th...
Source: NIH Extramural Nexus - June 9, 2021 Category: Research Authors: David Murray Tags: blog Open Mike Clinical Trials New Resources webinar Source Type: funding

An Updated Look at Applications Submitted During the Pandemic
In a previous post, we looked at the gender distribution of designated principal investigators (PI’s) of R01 and Research Project Grant (RPG) applications submitted before and after the onset of the COVID-19 pandemic. Since that time, we have paid close attention to the well-being of the extramural biomedical research workforce, in part through our survey of institutional leaders and scientists. Others have followed preprint postings and publications, finding evidence of the pandemic’s disproportionate effects. Here we look at NIH R01 and RPG application patterns for January 1 through April 8 over the past 6 years...
Source: NIH Extramural Nexus - June 1, 2021 Category: Research Authors: Mike Lauer Tags: blog Open Mike Award Programs COVID-19 Diversity Funding data R01 RPG Source Type: funding

Case Study in Review Integrity – The Professional Grant Writer
A series to raise awareness, encourage dialog and inspire creative problem solving for challenges in maintaining integrity in peer review.  The case study below reflects a real-life situation. ___________________________________________________________________________________ An NIH peer reviewer was approached by a well-known professional grant writing service to assist a client in preparing an NIH grant application.  The service advertised phenomenal success in securing NIH funding for its clients. The reviewer was concerned by the invitation.  He contacted an NIH official and asked whether participation with the serv...
Source: NIH Extramural Nexus - May 24, 2021 Category: Research Authors: Mike Lauer Tags: blog Open Mike case study conflict of interest in peer review Source Type: funding

How Many Researchers: The Positive Trend Continued into FY 2020
Now that fiscal year (FY) 2020 grants data are available in the NIH Data Book, let’s see how many unique scientists sought support on NIH research project grants (RPGs). The “cumulative investigator rate,” a person-based metric that looks at the likelihood that unique investigators are funded over a five-year window, has moved in a positive direction in recent years (see here for FYs 2019, 2018, and 2017), and we were pleased to see the trend mostly continue into FY 2020. Before diving into the 2020 data, a quick reminder about the NIH’s five-year cumulative investigator rate. To determine it, we take the number of...
Source: NIH Extramural Nexus - May 17, 2021 Category: Research Authors: Mike Lauer Tags: blog Open Mike biomedical research workforce cumulative investigator rate Source Type: funding

Enhancing Data Access and Analysis in the Cloud Advances NIH-Supported Discovery
Guest blog post authored by: Andrea Norris, MBA, Director, Center for Information Technology (CIT), and Chief Information Officer (CIO), NIH Patricia Flatley Brennan, RN, PhD, FAAN, Director, National Library of Medicine, NIH Susan Gregurick, PhD, Associate Director for Data Science, NIH; Director of the NIH Office of Data Science Strategy To fully benefit from the exponentially growing body of biomedical data, we need cutting-edge approaches that foster data access, analysis, sharing, and collaboration so novel scientific questions can be pursued. But the sheer volume, sometimes siloed nature, along with the costs and t...
Source: NIH Extramural Nexus - May 10, 2021 Category: Research Authors: Andrea Norris, Patti Brennan, Susan Gregurick, and Mike Lauer Tags: blog Open Mike Cloud Computing Open Access Resources rigor Source Type: funding

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Source: NIH Extramural Nexus - May 5, 2021 Category: Research Authors: NIH Staff Tags: Top Stories General Source Type: funding

Helping To Protect the Privacy of Participants in Non-NIH Funded Research
You likely know that for human-participant research funded wholly or in part by NIH, we automatically issue Certificates of Confidentiality (CoCs) as a term and condition of award. CoCs protect identifiable, sensitive information of people who participate from being disclosed to others not associated with the study. More about the CoC policy can be found on this blog and podcast. But, for human-participant research funded by an entity other than NIH, did you know that you can reach out to us to request a CoC as well? We offer this service for certain non-NIH funded projects to strengthen the privacy protections afforded t...
Source: NIH Extramural Nexus - April 27, 2021 Category: Research Authors: Mike Lauer Tags: blog Open Mike certificates of confidentiality COVID-19 human subjects Source Type: funding

FY 2020 By the Numbers: Extramural Investments in Research
Each year around this time we look back on NIH’s investment in research. Similar to previous fiscal years (FYs), this post focuses on grant funding and success rates for research supported through our traditional annual appropriations. Grants data related to special coronavirus appropriations are excluded here to be consistent with prior “By The Numbers” posts. For more on that spending, please review these posts and use the advanced search functionality available in RePORTER. NIH received $ 41.6 billion in FY 2020 (see our Appropriations history here ). Of this amount, $30.8 billion was awarded to 56,169 new and ren...
Source: NIH Extramural Nexus - April 21, 2021 Category: Research Authors: Mike Lauer Tags: blog Open Mike Funding data Source Type: funding

Why Properly Acknowledging NIH Support in Your Paper is Important
Imagine this scenario. In the hustle to publish a paper, you accidently forgot to cite the underlying NIH support. Or, the opposite, you opt to include that other grant in the acknowledgements that did not have anything to do with the work. No problem, right? Well, it could be. Accurately and precisely acknowledging NIH funding allows us to properly assess award outputs and make recommendations for future research directions. It is also a term and condition of award outlined in the NIH Grants Policy Statement. Since the Stevens Amendment passed in 1989, recipients have been required to acknowledge federal funding when publ...
Source: NIH Extramural Nexus - April 19, 2021 Category: Research Authors: Mike Lauer Tags: blog Open Mike Compliance publications Source Type: funding