Viruses, Vol. 15, Pages 1818: Nuclease Activity of the Jun & iacute;n Virus Nucleoprotein C-Terminal Domain
Viruses, Vol. 15, Pages 1818: Nuclease Activity of the Junín Virus Nucleoprotein C-Terminal Domain Viruses doi: 10.3390/v15091818 Authors: Alicia Armella Sierra María Eugenia Loureiro Sebastián Esperante Silvia Susana Borkosky Giovanna L. Gallo Gonzalo de Prat Gay Nora Lopez The mammarenavirus Junín (JUNV) is the causative agent of Argentine hemorrhagic fever, a severe disease of public health concern. The most abundant viral protein is the nucleoprotein (NP), a multifunctional, two-domain protein with the primary role as structural component of the viral nucleocapsids, used ...
Source: Viruses - August 26, 2023 Category: Virology Authors: Alicia Armella Sierra Mar ía Eugenia Loureiro Sebasti án Esperante Silvia Susana Borkosky Giovanna L. Gallo Gonzalo de Prat Gay Nora Lopez Tags: Article Source Type: research

Viruses, Vol. 15, Pages 369: Modulation of the Aryl Hydrocarbon Receptor Signaling Pathway Impacts on Jun & iacute;n Virus Replication
Viruses, Vol. 15, Pages 369: Modulation of the Aryl Hydrocarbon Receptor Signaling Pathway Impacts on Junín Virus Replication Viruses doi: 10.3390/v15020369 Authors: Miguel Angel Pelaez María Florencia Torti Aaron Ezequiel Alvarez De Lauro Agostina Belén Marquez Federico Giovannoni Elsa Beatriz Damonte Cybele Carina García Junín virus (JUNV), a member of the family Arenaviridae, is the etiological agent of the Argentine hemorrhagic fever, an endemic disease in the rural region of Argentina lacking a specific chemotherapy. Aryl hydrocarbon receptor (AHR) is expressed in sever...
Source: Viruses - January 28, 2023 Category: Virology Authors: Miguel Angel Pelaez Mar ía Florencia Torti Aaron Ezequiel Alvarez De Lauro Agostina Bel én Marquez Federico Giovannoni Elsa Beatriz Damonte Cybele Carina Garc ía Tags: Article Source Type: research

Mammarenavirus Genetic Diversity and Its Biological Implications
Curr Top Microbiol Immunol. 2023;439:265-303. doi: 10.1007/978-3-031-15640-3_8.ABSTRACTMembers of the family Arenaviridae are classified into four genera: Antennavirus, Hartmanivirus, Mammarenavirus, and Reptarenavirus. Reptarenaviruses and hartmaniviruses infect (captive) snakes and have been shown to cause boid inclusion body disease (BIBD). Antennaviruses have genomes consisting of 3, rather than 2, segments, and were discovered in actinopterygian fish by next-generation sequencing but no biological isolate has been reported yet. The hosts of mammarenaviruses are mainly rodents and infections are generally asymptomatic....
Source: Current Topics in Microbiology and Immunology - January 2, 2023 Category: Microbiology Authors: Manuela Sironi Diego Forni Juan C de la Torre Source Type: research