Alterations in Pre/Post Oxygenator Flows Due to Fibrin Deposition in the CardioHelp System-A Case Report
We present a 62-year-old patient with COVID-19 pneumonia on Veno-venous (VV) Extracorporeal Membrane Oxygenation (ECMO) with unique perturbations to pre and post oxygenator pressures due to fibrin deposition in despite being on a Heparin/Bivalirudin infusion and activated Partial Thromboplastin Time (aPTT) within therapeutic range of 60-80 seconds. On Day 8 of ECMO support, it was noticed that flows steadily decreased despite unchanged RPMs. Unlike typical blood flow to circuit pressure relationships, the circuit pressures did not correlate with the observed decreased flow. The Delta Pressure (ΔP) was not elevated. The pa...
Source: Journal of Extra-Corporeal Technology - February 6, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Tyler Wahl Angela Stokes Caleb Varner Burak Zeybek Amit Bardia Source Type: research
Anticoagulant Use During Extracorporeal Membrane Oxygenation Using Heparin and Direct Thrombin Inhibitors in COVID-19 and ARDS Patients
J Extra Corpor Technol. 2022 Sep;54(3):223-234. doi: 10.1182/ject-223-234.ABSTRACTCoagulopathies develop in patients supported with the use of extracorporeal membrane oxygenation (ECMO) and can be hemorrhagic and/or thrombophilic in spite of the use of systemic anticoagulation. The purpose this study was to examine the use of heparin and direct thrombin inhibitors (DTI) in COVID-19 patients with acute respiratory distress syndrome (ARDS) on ECMO, with a subset analysis by disease state. Following IRB approval, 570 consecutive records were reviewed of adult patients on venovenous ECMO between May 2020 and December 2021. Pat...
Source: Journal of Extra-Corporeal Technology - February 6, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Alfred H Stammers Eric A Tesdahl Shannon Barletti Linda Mongero Kirti Patel Matthew Mosca Anthony Sestokas Michael S Firstenberg Jeffrey P Jacobs Source Type: research
Alterations in Pre/Post Oxygenator Flows Due to Fibrin Deposition in the CardioHelp System-A Case Report
We present a 62-year-old patient with COVID-19 pneumonia on Veno-venous (VV) Extracorporeal Membrane Oxygenation (ECMO) with unique perturbations to pre and post oxygenator pressures due to fibrin deposition in despite being on a Heparin/Bivalirudin infusion and activated Partial Thromboplastin Time (aPTT) within therapeutic range of 60-80 seconds. On Day 8 of ECMO support, it was noticed that flows steadily decreased despite unchanged RPMs. Unlike typical blood flow to circuit pressure relationships, the circuit pressures did not correlate with the observed decreased flow. The Delta Pressure (ΔP) was not elevated. The pa...
Source: Journal of Extra-Corporeal Technology - February 6, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Tyler Wahl Angela Stokes Caleb Varner Burak Zeybek Amit Bardia Source Type: research
Anticoagulant Use During Extracorporeal Membrane Oxygenation Using Heparin and Direct Thrombin Inhibitors in COVID-19 and ARDS Patients
J Extra Corpor Technol. 2022 Sep;54(3):223-234. doi: 10.1182/ject-223-234.ABSTRACTCoagulopathies develop in patients supported with the use of extracorporeal membrane oxygenation (ECMO) and can be hemorrhagic and/or thrombophilic in spite of the use of systemic anticoagulation. The purpose this study was to examine the use of heparin and direct thrombin inhibitors (DTI) in COVID-19 patients with acute respiratory distress syndrome (ARDS) on ECMO, with a subset analysis by disease state. Following IRB approval, 570 consecutive records were reviewed of adult patients on venovenous ECMO between May 2020 and December 2021. Pat...
Source: Journal of Extra-Corporeal Technology - February 6, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Alfred H Stammers Eric A Tesdahl Shannon Barletti Linda Mongero Kirti Patel Matthew Mosca Anthony Sestokas Michael S Firstenberg Jeffrey P Jacobs Source Type: research
Alterations in Pre/Post Oxygenator Flows Due to Fibrin Deposition in the CardioHelp System-A Case Report
We present a 62-year-old patient with COVID-19 pneumonia on Veno-venous (VV) Extracorporeal Membrane Oxygenation (ECMO) with unique perturbations to pre and post oxygenator pressures due to fibrin deposition in despite being on a Heparin/Bivalirudin infusion and activated Partial Thromboplastin Time (aPTT) within therapeutic range of 60-80 seconds. On Day 8 of ECMO support, it was noticed that flows steadily decreased despite unchanged RPMs. Unlike typical blood flow to circuit pressure relationships, the circuit pressures did not correlate with the observed decreased flow. The Delta Pressure (ΔP) was not elevated. The pa...
Source: Journal of Extra-Corporeal Technology - February 6, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Tyler Wahl Angela Stokes Caleb Varner Burak Zeybek Amit Bardia Source Type: research
