Anticoagulation in critically ill patients on mechanical ventilation suffering from COVID-19 disease, The ANTI-CO trial: A structured summary of a study protocol for a randomised controlled trial
AbstractObjectivesTo assess the effect of anticoagulation with bivalirudin administered intravenously on gas-exchange in patients with COVID-19 and respiratory failure using invasive mechanical ventilation.Trial designThis is a single centre parallel group, superiority, randomized (1:1 allocation ratio) controlled trial.ParticipantsAll patients admitted to the Hamad Medical Corporation -ICU in Qatar for COVID-19 associated respiratory distress and in need of mechanical ventilation are screened for eligibility.Inclusion criteria: all adult patients admitted to the ICU who test positive for COVID-19 by PCR-test and in need f...
Source: Trials - September 7, 2020 Category: Research Source Type: clinical trials

Efficacy and Safety of Bivalirudin Versus Heparin During Coil Embolization in Patients With Ruptured Intracranial Aneurysms
Condition:   Subarachnoid Hemorrhage, Aneurysmal Interventions:   Drug: Bivalirudin 250 MG Injection;   Drug: Heparin Sponsors:   Changhai Hospital;   The First Affiliated Hospital of Zhengzhou University;   Zhejiang University;   Wuhan University;   Qilu Hospital of Shandong University;   The First People's Hospital of Changzhou Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - August 31, 2020 Category: Research Source Type: clinical trials

Safety and Efficacy of Bivalirudin During Short-term Intervention of Non-infarction Related Artery After PPCI of STEMI
Condition:   STEMI With Multivessel Coronary Disease Interventions:   Drug: Bivalirudin;   Drug: Heparin Sponsors:   First Affiliated Hospital Xi'an Jiaotong University;   Shaanxi Provincial People's Hospital;   Hanzhong Central Hospital;   Yan'an University Affiliated Hospital;   Xianyang Central Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 17, 2020 Category: Research Source Type: clinical trials

Multi-center Application of Bivalirudin in Left Atrial Appendage Occlusion
Condition:   Evaluate the Safety and Efficacy of Bivalirudin in Decreasing Bleeding Risk Interventions:   Drug: Bivalirudin;   Drug: Heparin Sponsor:   Shanghai Zhongshan Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 12, 2019 Category: Research Source Type: clinical trials

Bivalirudin in Late PCI for STEMI
Condition:   we Focuse on the Efficiency and Safety for Bivalirudin as the Anticoagulation Therapy During Late PCI Interventions:   Drug: Bivalirudin;   Drug: Heparin Sponsor:   Second Xiangya Hospital of Central South University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 4, 2019 Category: Research Source Type: clinical trials

Bivalirudin in Late PCI for Oatients With STEMI
Condition:   we Focuse on the Efficiency and Safety of Bivalirudin During Late PCI Interventions:   Drug: Bivalirudin;   Drug: Heparin Sponsor:   Second Xiangya Hospital of Central South University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 4, 2019 Category: Research Source Type: clinical trials

Bivalirudin in Late PCI for Oatients With STEMI
Condition:   STEMI - ST Elevation Myocardial Infarction Interventions:   Drug: Bivalirudin;   Drug: Heparin Sponsor:   Second Xiangya Hospital of Central South University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 4, 2019 Category: Research Source Type: clinical trials

Safety and Efficacy of Delayed Continuous Use of Bivalirudin 4 Hours After ePCI (COBER Study)
Condition:   Coronary Heart Disease Interventions:   Drug: delayed continuous use of bivalirudin;   Drug: bivalirudin use during ePCI Sponsor:   Nanjing First Hospital, Nanjing Medical University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 9, 2019 Category: Research Source Type: clinical trials