Daptomycin versus placebo as an adjunct to beta-lactam therapy in the treatment of Staphylococcus aureus bacteremia: study protocol for a randomized controlled trial
DiscussionThe DASH-RCT will compare the use of daptomycin as an adjunct to an anti-staphylococcal beta-lactam versus placebo in the treatment of MSSA bacteremia. We believe that a short course of dual therapy will result in earlier eradication of bacteremia and that subsequent research could evaluate effects on metastatic infection, relapse, and/or mortality. Ongoing issues in the trial include a delay between presentation of infection, enrollment in the trial, and the potential for unrecognized deep foci of infection at diagnosis.Trial registrationClinicalTrials.gov,NCT02972983. Registered on 25 November 2016.Trial protoc...
Source: Trials - May 29, 2018 Category: Research Source Type: clinical trials
Use of Dexamethasone in Prevention of the Second Phase or a Biphasic Reaction of Anaphylaxis
Condition: Mild -Moderate Anaphylaxis - Symptoms That Affect the Skin With Cardiovascular, Respiratory or Gastrointestinal Involvement, But no Signs of Hypotension ,Laryng Intervention: Drug: Dexamethasone Oral Sponsor: Hamad Medical Corporation Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 14, 2018 Category: Research Source Type: clinical trials
