Building Infrastructure for Precision Medicine Research on Minority Health and Disparities in Alzheimers Disease (AD) and AD-Related Dementias (ADRD) (UH2/UH3 Clinical Trial Not Allowed)
Funding Opportunity RFA-AG-23-020 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity is to promote collaborative research programs to support the development of infrastructure for precision medicine approaches for minority health and health disparities in AD/ADRD. This FOA serves as a catalytic opportunity for investigators to focus on populations underrepresented in AD/ADRD research, to build resources that include neurobiological, environmental, behavioral, and social science data, and to initiate innovative, integrated, and expanded studies of individuals from these populations. (Sou...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 8, 2022 Category: Research Source Type: funding

Alzheimer's-related Resource Centers for Minority Aging Research (AD/ADRD RCMAR) (P30 Clinical Trial Optional)
Funding Opportunity RFA-AG-23-025 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications from institutions proposing to develop, or renew, a Resource Center for Minority Aging Research (RCMAR) that focuses on behavioral and social science research in a key area related to Alzheimers disease (AD) and AD-related dementias (ADRD). The goal of the AD/ADRD RCMAR program is two-fold: (1) to diversify the AD/ADRD research workforce in priority areas of social, behavioral, psychological, and economic research related to AD/ADRD by mentoring promising scientists from diverse...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 5, 2022 Category: Research Source Type: funding

Resource Centers for Minority Aging Research (RCMAR) Coordinating Center (U24 Clinical Trial Optional)
Funding Opportunity RFA-AG-23-027 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to develop and maintain a coordinating center (CC) for the Resource Centers for Minority Aging Research (RCMAR) program. The RCMAR program supports behavioral and social research on aging, health disparities in older adults, and Alzheimers disease and Alzheimers disease related dementias (AD/ADRD), through the development of research infrastructure and mentorship of early career scientists from diverse backgrounds. The primary responsibilities of the RCMAR CC are to: coordinate and...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 5, 2022 Category: Research Source Type: funding

Early-Stage Therapy Development for ADRD (R61/R33 Clinical Trial Not Allowed)
Funding Opportunity RFA-NS-22-059 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) encourages early-stage development of novel small molecule or biologic therapeutics for NINDS mission-relevant? Alzheimer's and related dementias: frontotemporal degeneration (FTD, including Picks disease and progressive supranuclear palsy), Lewy body dementias (LBD; including dementia with Lewy bodies (DLB) and Parkinsons disease dementia (PDD), vascular contributions to cognitive impairment and dementia (VCID), and multiple etiology dementias (MED). This FOA covers four stages of early therapy dis...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 2, 2022 Category: Research Source Type: funding

Notice of Change to the Maximum Salary for Clinician-Scientists for PAR-22-022 NINDS Alzheimers Disease and Alzheimers Disease-Related Dementias (AD/ADRD) Advanced Postdoctoral Career Transition Award to Promote Diversity (K99/R00)
Notice NOT-NS-22-109 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 26, 2022 Category: Research Source Type: funding

Cellular and Molecular Mechanisms of Prion-Like Aggregate Seeding, Propagation, and Neurotoxicity in AD/ADRD (R01 Clinical Trial Not Allowed)
Funding Opportunity PAR-23-023 from the NIH Guide for Grants and Contracts. The accumulation of misfolded proteins in the brain is a key pathological feature shared by many neurodegenerative diseases that can result in dementia such as Alzheimers Disease, Lewy Body Diseases, Frontotemporal Degeneration, and cerebral amyloid angiopathy. Classical prion diseases such as Creutzfeldt-Jakob Disease are a rare family of neurodegenerative disorders that occur when the cellular prion protein (PrPC) undergoes structural conversion to a pathological form (PrPSc), which is usually triggered by its interaction with an infectious va...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 25, 2022 Category: Research Source Type: funding

Functional Target Validation for Alzheimer's Disease-Related Dementias (ADRDs) (R61/R33 Clinical Trial Not Allowed)
Funding Opportunity RFA-NS-22-055 from the NIH Guide for Grants and Contracts. This FOA invites applications that propose the comprehensive functional validation of newly identified therapeutic target candidates for Alzheimer's Disease-Related Dementias (ADRDs). This FOA seeks to promote critical target validation approaches to help de-risk subsequent translational research and accelerate the advancement of novel therapies for ADRD. Target(s) or molecular pathway(s) to be considered for validation must have been already identified using tissue expression or genetic data generated in human samples. In its initial phase, ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 21, 2022 Category: Research Source Type: funding

More Monitoring of Cognitive Change, Continued (M3C3) (U2C Clinical Trial Optional)
Funding Opportunity RFA-AG-23-021 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications to expand the content, design, and implementation of research infrastructure funded under FOA RFA-AG-18-012 Mobile Monitoring of Cognitive Change (U2C), also known as the Mobile Toolbox (MTB) Project. The expansion aims to (1) add assessments on mobile devices of non-cognitive socioemotional psychological functions, health states, and contextual factors that may modify cognitive performance; and (2) enable widespread dissemination and support for use of the tools developed for m...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 11, 2022 Category: Research Source Type: funding

Notice of Special Interest: Alzheimers-Focused Administrative Supplements for NIH Grants that are Not Focused on Alzheimers Disease
Notice NOT-AG-22-025 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 7, 2022 Category: Research Source Type: funding

Impact of the Microbiome-Gut-Brain Axis on Alzheimer's Disease and Alzheimer's Disease-Related Dementias (R01 Clinical Trial Not Allowed)
Funding Opportunity PAR-22-211 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications for basic and translational research on the impact of the microbiome on Alzheimers Disease and Alzheimers Disease Related Dementias (AD/ADRD). While there is growing evidence that the microbiome is an important factor that contributes to overall health and a variety of diseases and disorders, the role of the alimentary canaland other sources of endogenous microbiota in specific AD/ADRDs has not been adequately addressed. This FOA will support mechanistic research focused on a more ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 5, 2022 Category: Research Source Type: funding

Structural Biology of Alzheimer's Disease Related Dementias (ADRDs) Proteinopathies (R01 Clinical Trial Not Allowed)
Funding Opportunity PAR-22-208 from the NIH Guide for Grants and Contracts. The purpose of the FOA is to support the structural characterization of protein species associated with Alzheimer's Disease Related Dementias (ADRDs) through the utilization of cryo-electron microscopy (cryo-EM) and cryo-electron tomography (cryo-ET) of proteins expressed in human tissue and cell sources. Studies in response to this RFA should also include the development of research tools and resources to further characterize/validate the protein species. This FOA is in response to the Alzheimer's Disease Related Dementias (ADRD) challenges out...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 27, 2022 Category: Research Source Type: funding

Transformative Artificial Intelligence and Machine Learning Based Strategies to Identify Determinants of Exceptional Health and Life Span (R21/R33 Clinical Trial Not Allowed)
Funding Opportunity RFA-AG-23-033 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications seeking to develop novel, transformative artificial intelligence/machine learning (AI/ML) strategies, and computer automation, to integrate, extract, and interpret multi-omic (i.e., genome, epigenome, transcriptome, proteome, metabolome, microbiome, phenome) data sets from human exceptional longevity (EL) cohorts and multiple non-human species that display wide variation in life span and decipher the relationships between DNA, RNA, proteins, metabolites, and other cell variables...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 22, 2022 Category: Research Source Type: funding

Advancing Research on Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) (R43/R44 Clinical Trial Optional)
Funding Opportunity PAS-22-196 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications to the National Institute on Aging's (NIA) Small Business Innovation Research (SBIR) program. The aim of this FOA is to support research that may lead to the development of innovative products and/or services that have the potential to advance progress in preventing and treating Alzheimer's disease (AD) and AD-related dementias (ADRD) and/or caring for and treating patients living with AD/ADRD. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 21, 2022 Category: Research Source Type: funding

Advancing Research on Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) (R41/R42 Clinical Trial Optional)
Funding Opportunity PAS-22-197 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications to the National Institute on Aging's (NIA) Small Business Technology Transfer Research (STTR) program. The aim of this FOA is to support research that may lead to the development of innovative products and/or services with the potential to advance progress in preventing and treating Alzheimer's disease (AD) and AD-related dementias (ADRD) and/or caring for and treating patients living with AD/ADRD. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 21, 2022 Category: Research Source Type: funding

Network for Personalization of Diagnostic Tests for Alzheimers Disease (AD) and Alzheimers Disease-Related Dementias (ADRD) in Older Adults with Multiple Chronic Conditions (MCCs) (U24 Clinical Trial Optional)
Funding Opportunity RFA-AG-23-032 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications to establish a network that will conduct transdisciplinary aging diagnostic biomarker and/or imaging research projects focused on Alzheimers Disease and Alzheimers Disease-Related Dementias (AD/ADRD) in persons living with Multiple Chronic Conditions (MCCs). The aim of the research is to better align diagnostic testing with the needs and priorities of an aging population. The national consortium will: 1) assemble existing data and acquire real-world data to ensure that the resea...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 14, 2022 Category: Research Source Type: funding