Topical Liposomal Amphotericin B Gel Treatment for Cutaneous Leishmaniasis
Condition: LeishmaniasisInterventions: Drug: Topical Amphotericin-B 0.4% liposomal gel; Drug: PlaceboSponsor: Soroka University Medical CenterNot yet recruiting - verified November 2015 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 13, 2016 Category: Research Source Type: clinical trials
AMBITION- cm : intermittent high dose AmBisome on a high dose fluconazole backbone for cryptococcal meningitis induction therapy in sub-Saharan Africa: study protocol for a randomized controlled trial
This study examines whether short-course high-dose liposomal amphotericin B (AmBisome), given with high dose fluconazole, is non-inferior (in terms of microbiological and clinical endpoints) to standard-dose 14-day courses of AmBisome plus high dose fluconazole for treatment of HIV-associated CM.
Methodology/design
This is an adaptive open-label phase II/III randomised non-inferiority trial comparing alternative short course AmBisome regimens. Step 1 (phase II) will compare four treatment arms in 160 adult patients (≥18 years old) with...
Source: Trials - June 17, 2015 Category: Research Source Type: clinical trials
Cost-Effectiveness of Amphotericin B
Condition: Invasive Fungal InfectionsIntervention: Other: None interventionSponsor: Hospital Universitario Evangelico de CuritibaNot yet recruiting - verified August 2015 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 20, 2015 Category: Research Source Type: clinical trials
