A mitochondria-targeted probe containing multi-rotors for visualizing the viscosity change in living cells
Shuting Shen, Kun Yu, Yaxuan Wang, Zhiyu Wang, Lei Hu, Hui Wang (1) MV-indol can quantitatively detect viscosity with a high selectivity and a 75-fold enhancement in QY. (2) The mechanism for detection viscosity was confirmed by TD-DFT. (3) MV-indol can precisely localize in mitochondria and monitor the change of mitochondrial viscosity at the cellular level.
Source: Australian Journal of Chemistry - Category: Chemistry Authors: Shuting Shen Kun Yu Yaxuan Wang Zhiyu Wang Lei Hu Hui Wang Source Type: research