Individualized References of Carotid Stiffening Quantified With Ultrafast Ultrasound Imaging: Model Construction and Preliminary Validation

To establish and preliminarily validate an individualized reference of carotid stiffness quantified by ultrafast pulse wave velocity (ufPWV), our study included 225 healthy individuals in the modeling cohort and 628 individuals in the validation cohort. All participants underwent assessment of carotid intima –media thickness (cIMT), pulse wave velocity–beginning of systole and pulse wave velocity–end of systole (PWV-ES). A threshold equation of estimated PWV-ES was obtained by multiple linear regression analysis in the modeling cohort as follows: estimated PWV-ES (m/s) = 0.080 × age (y) + 0 .767 × low-density lipoprotein (mmol/L) + 0.040 × systolic blood pressure (mm Hg) + 0.372 × sex (male = 1, female = 0) – 2.803.

Source: Ultrasound in Medicine and Biology - May 18, 2022 Category: Radiology Authors: Yinping Wang, Zhengqiu Zhu, Xuehui Ma, Wenjun Liu, Xuezhong Jiang, Yiyun Wu, Chong Zou, Bixiao Shen, Hongye Sun, Hui Gao, Yun Luan, Hui Huang Tags: Original Contribution Source Type: research