Oral vitamin D3 supplementation for femtosecond LASIK-associated dry eye vitamin D for LASIK dry eye syndrome

AbstractPurposeTo assess the effect of oral vitamin D3 supplementation in dry eye after femtosecond laser-assistedin situ keratomileusis (FS-LASIK).SettingLiuzhou Worker ’s Hospital.DesignThis prospective study included 90 patients selected between January and December in 2019, who underwent FS-LASIK operation in our hospital and had obvious symptoms indicating dry eyes 1  month after operation. The subjects were randomly divided into two groups: The experimental group (n = 45) received vitamin D3 2000 IU/D continuously for 12 weeks; the control group (n = 45) did not take vitamin D3 orally. Ocular surface disease index (OSDI), Tear breakup time (TBUT) and Schirmer’s test I were evaluated premedication and 1,3,6 months after treatment. Serum vitamin D3 level and the mean concentration of cytokine IL-6, IL-17, IL-23 int ears were also measured.ResultsOne month after treatment, the mean OSDI score of the experimental group (11.67  ± 8.53) was significantly lower than that of the control group (23.82 ± 13.22) (P  =  0.007). TBUT (10.71 ± 1.02 s) and Schirmer I (9.36 ± 0.40 mm) of the experimental group were higher than those of the control group (7.49 ± 1.29 s and 7.51 ± 0.44 mm). The OSDI (10.25 ± 5.49) was significantly lower than those of the control group(20.22 ± 6.23) a nd TBUT (10.75 ± 1.09 s) and Schirmer I test value (11.34 ± 0.39 mm) of the experimental group were significantly higher than those...
Source: International Ophthalmology - Category: Opthalmology Source Type: research