Challenges of the treatment of pediatric hepatosplenic bartonellosis: case report and literature review

In this report, a 12-year-old girl diagnosed with HS-CSD and unresponsive to primary treatment with macrolide group antibiotic was presented. The patient had liver findings compatible with CSD, confirmed radiologically and pathologically, andBartonella henselae indirect immunofluorescence assay IgG was positive at 1/2048 titre. A combination therapy for six months with doxycycline and rifampicin was initiated, and the patient was successfully treated. The preference for monotherapy or combination regimen in HS-CSD is predominantly determined by the clinician according to the severity of the patient ’s clinical findings. The effectivity of antimicrobial regimen in HS-CSD requires further investigation.
Source: The Journal of Infection in Developing Countries - Category: Infectious Diseases Source Type: research