Pd1-06 effect of onabotulinumtoxina treatment for neurogenic detrusor over activity on the prevention of autonomic dysreflexia following spinal cord injury

Neurogenic detrusor overactivity (NDO) is a leading cause of autonomic dysreflexia (AD) in spinal cord injury (SCI). Subjective improvements in AD has been observed following OnabotulinumtoxinA (Botox©) treatment for NDO but no studies have quantitatively assessed the capacity of Botox to reduce AD frequency and severity using the clinical cut-off of an increase in systolic blood pressure (SBP) of ≥20 mmHg.

Source: The Journal of Urology - April 1, 2015 Category: Urology & Nephrology Authors: Renee Fougere, Katharine Currie, Lynn Stothers, Mark Nigro, Daniel Rapaport, Andrei Krassioukov Tags: Urodynamics/Incontinence/Female Urology: Neurogenic Voiding Dysfunction I Source Type: research