Pd45-07 a comparison of estradiol levels and gynecomastia rates in hypogonadal men using clomiphene citrate versus transdermal testosterone

Clomiphene citrate (CC) is recognized as a management strategy in men with hypogonadism (HG). Some concern exists regarding its ability to raise serum estradiol (E2) levels given its mechanism of action. Serum total testosterone (TT) may be converted to E2 by aromatase irrespective of which T replacement therapy (TRT) modality is used. This analysis was undertaken to compare serum E2 levels in men with HG using CC versus transdermal T (TDT).
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Tags: Sexual Function/Dysfunction/Andrology: Medical and Non-Surgical Therapy II Source Type: research