Caution advised in the use of CFTR modulator treatment for individuals harboring specific CFTR variants

Cystic fibrosis (CF) is caused by dysfunction or absence of the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Over 2,000 known variants exist in the CFTR gene.

Source: Journal of Cystic Fibrosis - May 5, 2022 Category: Respiratory Medicine Authors: Karen S. Raraigh, Michelle H. Lewis, Joseph M. Collaco, Mary Corey, Christopher M. Penland, Anne L. Stephenson, Johanna M. Rommens, Carlo Castellani, Garry R. Cutting Tags: Short Communication Source Type: research