Lactate kinetics and mitochondrial respiration in skeletal muscle of healthy humans under influence of adrenaline

In conclusion a 3-compartment model gives additional information to the 2-compartment model but due to its larger variation and invasive muscle biopsy it is less likely to become a regularly used tool in clinical research. Hyperlactatemia in response to adrenergic stimuli was driven by an elevated lactate release from skeletal muscle most likely due to a redirection of a high intramuscular turnover rather than an increased production.

Source: Clinical Science - April 1, 2015 Category: Biomedical Science Authors: J Grip, T Jakobsson, C Hebert, M Klaude, G Sandström, J Wernerman, O Rooyackers Source Type: research