ROCK inhibitor fasudil reduces the expression of inflammatory factors in LPS-induced rat pulmonary microvascular endothelial cells via ROS/NF- κB pathway

Inflammation plays a major role in the pulmonary artery hypertension (PAH) and the acute lung injury (ALI) diseases. The common feature of these complications is the dysfunction of pulmonary microvascular endo...

Source: BMC Clinical Pharmacology - April 15, 2022 Category: Drugs & Pharmacology Authors: Huanlong Liu, Zhenhua Pan, Xindi Ma, Junru Cui, Juan Gao, Qingfeng Miao, Zhongning Zhu, Xueyan Chen and Suwen Su Tags: Research Source Type: research