Multimarker synaptic protein cerebrospinal fluid panels reflect TDP-43 pathology and cognitive performance in a pathological cohort of frontotemporal lobar degeneration

Synapse degeneration is an early event in pathological frontotemporal lobar degeneration (FTLD). Consequently, a surrogate marker of synapse loss could be used to monitor early pathologic changes in patients w...

Source: Molecular Neurodegeneration - April 8, 2022 Category: Neurology Authors: Alba Cervantes Gonz ález, David J. Irwin, Daniel Alcolea, Corey T. McMillan, Alice Chen-Plotkin, David Wolk, Sònia Sirisi, Oriol Dols-Icardo, Marta Querol-Vilaseca, Ignacio Illán-Gala, Miguel Angel Santos-Santos, Juan Fortea, Edward B. Lee, John Q. Tro Tags: Research article Source Type: research