β-Hydroxy-β-Methylbutyrate Supplementation May Not Enhance Additional Effects of Exercise on Muscle Quality in Older Women

Purpose The combined treatment effects of nutritional supplementation and exercise on muscle quality (MQ) remain unexamined in individuals at risk for sarcopenia. This secondary analysis aimed to test whether β-hydroxy-β-methylbutyrate (HMB) supplementation enhances the effects of resistance training (RT) on MQ in older women with low muscle mass. Methods This randomized, double-blind, placebo-controlled, two-by-two factorial design trial was conducted at the Tokyo Metropolitan Institute of Gerontology. Women age 65–79 yr with a skeletal muscle mass index of
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: BASIC SCIENCES Source Type: research