Framework for the synthesis of non-randomised studies and randomised controlled trials: a guidance on conducting a systematic review and meta-analysis for healthcare decision making

Conclusion: Our framework augments existing guidance on assessing the quality of NRS and their compatibility with RCTs for evidence synthesis, while also highlighting potential challenges in implementing it. This manuscript received endorsement from the International Society for Pharmacoepidemiology.

Source: Evidence-Based Medicine - March 23, 2022 Category: Internal Medicine Authors: Sarri, G., Patorno, E., Yuan, H., Guo, J., Bennett, D., Wen, X., Zullo, A. R., Largent, J., Panaccio, M., Gokhale, M., Moga, D. C., Ali, M. S., Debray, T. P. A. Tags: Open access, General Medicine Evidence synthesis Source Type: research