Unilateral Multifocal Choroidal Melanoma with Underlying Isolated Choroidal Melanocytosis

We describe three cases of patients who developed unilateral, multifocal uveal melanoma in the setting of underlying isolated choroidal melanocytosis. All patients developed either two distinct tumors at presentation or a new discrete choroidal melanoma arising from the choroidal melanocytosis over 1 year following treatment of the original tumor by plaque brachytherapy. These cases provide additional evidence of the association between isolated choroidal melanocytosis and uveal melanoma, and suggest increased risk of multifocal melanoma in patients with this condition.
Source: Ocular Oncology and Pathology - Category: Opthalmology Source Type: research