Superior segmental optic nerve hypoplasia: A review
Superior segmental optic nerve hypoplasia (SSONH) is a congenital condition characterized by developmental abnormalities of the superior optic disc and an underappreciated differential diagnosis for glaucoma. The reported prevalence is less than 1%, although likely underestimated due to the difficulties with diagnosis. The exact pathophysiology of SSONH remains elusive, but a mechanism involving developmental attrition of retinal ganglion cells has been proposed, and maternal diabetes is recognized as a major risk factor.
Source: Survey of Ophthalmology - Category: Opthalmology Authors: Jo-Hsuan Wu, Chao-Wen Lin, Chun-Hsiu Liu, Robert N. Weinreb, Derek S. Welsbie Tags: Review article Source Type: research