Epistatic genetic interactions govern morphogenesis during sexual reproduction and infection in a global human fungal pathogen [Genetics]
Cellular development is orchestrated by evolutionarily conserved signaling pathways, which are often pleiotropic and involve intra- and interpathway epistatic interactions that form intricate, complex regulatory networks. Cryptococcus species are a group of closely related human fungal pathogens that grow as yeasts yet transition to hyphae during sexual reproduction. Additionally, during...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Sheng Sun, Cullen Roth, Anna Floyd Averette, Paul M. Magwene, Joseph Heitman Tags: Genetics Biological Sciences Source Type: research