Predicting the Drug Clearance Pathway with Structural Descriptors

ConclusionThe developed model can be used to find the clearance pathways of new drug candidates with acceptable accuracy. The main descriptors that are used to evaluate this parameter are the hydrophobicity and the number of hydrogen-bonding functional groups of the compound.
Source: European Journal of Drug Metabolism and Pharmacokinetics - Category: Drugs & Pharmacology Source Type: research